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Institution

University of Zagreb

EducationZagreb, Grad Zagreb, Croatia
About: University of Zagreb is a education organization based out in Zagreb, Grad Zagreb, Croatia. It is known for research contribution in the topics: Population & European union. The organization has 21769 authors who have published 50267 publications receiving 783239 citations. The organization is also known as: Zagreb University & Sveučilište u Zagrebu.


Papers
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Journal ArticleDOI
Ana Budimir1
TL;DR: In this article, a series of 8-hydroxyquinoline analogues have been investigated for their potential to treat neurodegeneration, and showed the greatest potential for the treatment of neuro-degenerative diseases.
Abstract: In the last few years, various studies have been providing evidence that metal ions are critically involved in the pathogenesis of major neurological diseases (Alzheimer, Parkinson). Metal ion chelators have been suggested as potential therapies for diseases involving metal ion imbalance. Neurodegeneration is an excellent target for exploiting the metal chelator approach to therapeutics. In contrast to the direct chelation approach in metal ion overload disorders, in neurodegeneration the goal seems to be a better and subtle modulation of metal ion homeostasis, aimed at restoring ionic balance. Thus, moderate chelators able to coordinate deleterious metals without disturbing metal homeostasis are needed. To date, several chelating agents have been investigated for their potential to treat neurodegeneration, and a series of 8-hydroxyquinoline analogues showed the greatest potential for the treatment of neurodegenerative diseases.

166 citations

Journal ArticleDOI
TL;DR: SamEx, a mobile learning system used by 305 students in formal and informal learning in a primary school in Singapore, is examined to examine how the usage of tools such as SamEx predicts students' science examination results, the role of badges as an extrinsic motivational tool, and how individual and collaborative learning emerge.
Abstract: This study presents and examines SamEx, a mobile learning system used by 305 students in formal and informal learning in a primary school in Singapore. Students use SamEx in situ to capture media such as pictures, video clips and audio recordings, comment on them, and share them with their peers. In this paper we report on the experiences of students in using the application throughout a one-year period with a focus on self-directedness, quality of contributions, and answers to contextual question prompts. We examine how the usage of tools such as SamEx predicts students' science examination results, discuss the role of badges as an extrinsic motivational tool, and explore how individual and collaborative learning emerge. Our research shows that the quantity and quality of contributions provided by the students in SamEx predict the end-year assessment score. With respect to specific system features, contextual answers given by the students and the overall likes received by students are also correlated with the end-year assessment score. Answers given and likes received predict the total assessment score.Introduction of more collaboration software features could impact students' results.Engaging in self-directed activities helps students in their learning.Badges can motivate students to learn when teachers provide learning contexts.Intentional teacher-directed tasks stimulate students to participate.

166 citations

Journal ArticleDOI
TL;DR: The dramatic reduction of the dimensions and the better crystal shape, together with the presence of the hydrophilic polymer determined a remarkable enhancement of the in vitro drug dissolution rate.

166 citations

Journal ArticleDOI
TL;DR: In vitro release studies of liposomes incorporated in these gels confirmed their applicability as a novel drug carrier system in vaginal delivery and it was possible to achieve an adequate pH value corresponding to physiological conditions as well as desirable viscosity.

166 citations

Journal ArticleDOI
TL;DR: Glycans are involved in virtually all physiological processes, and inter-individual variation in glycome composition is large, and these differences associate with disease risk, disease course and the response to therapy.

166 citations


Authors

Showing all 22096 results

NameH-indexPapersCitations
Harry Campbell150897115457
Joseph R. Ecker14838194860
Igor Rudan142658103659
Nikola Godinovic1381469100018
Ivica Puljak134143697548
Damir Lelas133135493354
Željko Ivezić12934484365
Piotr Ponikowski120762131682
Marin Soljacic11776451444
Ivan Dikic10735952088
Ozren Polasek10243652674
Mordechai Segev9972940073
Srdan Verstovsek96104538936
Segev BenZvi9548232127
Mirko Planinic9446731957
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023119
2022529
20213,277
20203,360
20193,176
20183,042