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Institution

Vrije Universiteit Brussel

EducationBrussels, Belgium
About: Vrije Universiteit Brussel is a education organization based out in Brussels, Belgium. It is known for research contribution in the topics: Population & Context (language use). The organization has 14295 authors who have published 38258 publications receiving 1203970 citations. The organization is also known as: VUB.


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Journal ArticleDOI
TL;DR: In this article, the collective interactions among the simplest, biologically relevant proteins and archetypal RNA molecules are sufficient for driving the spontaneous emergence of multilayered condensates with distinct material properties.
Abstract: Phase separation of multivalent protein and RNA molecules underlies the biogenesis of biomolecular condensates such as membraneless organelles. In vivo, these condensates encompass hundreds of distinct types of molecules that typically organize into multilayered structures supporting the differential partitioning of molecules into distinct regions with distinct material properties. The interplay between driven (active) versus spontaneous (passive) processes that are required for enabling the formation of condensates with coexisting layers of distinct material properties remains unclear. Here, we deploy systematic experiments and simulations based on coarse-grained models to show that the collective interactions among the simplest, biologically relevant proteins and archetypal RNA molecules are sufficient for driving the spontaneous emergence of multilayered condensates with distinct material properties. These studies yield a set of rules regarding homotypic and heterotypic interactions that are likely to be relevant for understanding the interplay between active and passive processes that control the formation of functional biomolecular condensates.

315 citations

Journal ArticleDOI
TL;DR: In this paper, the role of brain monoaminergic neurotransmitter systems in whole-body endurance performance is discussed, particularly with regard to exercise in hot environments, and some of the neural changes that accompany exercise and the development of fatigue are discussed.
Abstract: During exercise, there is a progressive reduction in the ability to produce muscle force. Processes within the nervous system as well as within the muscles contribute to this fatigue. In addition to impaired function of the motor system, sensations associated with fatigue and impairment of homeostasis can contribute to the impairment of performance during exercise. This review discusses some of the neural changes that accompany exercise and the development of fatigue. The role of brain monoaminergic neurotransmitter systems in whole-body endurance performance is discussed, particularly with regard to exercise in hot environments. Next, fatigue-related alterations in the neuromuscular pathway are discussed in terms of changes in motor unit firing, motoneuron excitability, and motor cortical excitability. These changes have mostly been investigated during single-limb isometric contractions. Finally, the small-diameter muscle afferents that increase firing with exercise and fatigue are discussed. These afferents have roles in cardiovascular and respiratory responses to exercise, and in the impairment of exercise performance through interaction with the motor pathway, as well as in providing sensations of muscle discomfort. Thus, changes at all levels of the nervous system, including the brain, spinal cord, motor output, sensory input, and autonomic function, occur during exercise and fatigue. The mix of influences and the importance of their contribution vary with the type of exercise being performed.

315 citations

Journal ArticleDOI
TL;DR: In this paper, the authors introduce a general method to prove uniform in bandwidth consistency of kernel-type function estimators, such as the kernel density estimator, the Nadaraya-Watson regression estimator and the conditional empirical process.
Abstract: We introduce a general method to prove uniform in bandwidth consistency of kernel-type function estimators. Examples include the kernel density estimator, the Nadaraya–Watson regression estimator and the conditional empirical process. Our results may be useful to establish uniform consistency of data-driven bandwidth kernel-type function estimators.

314 citations

Journal ArticleDOI
TL;DR: Clinical relevant criteria that can help to guide the physician in the management of patients with impaired or poor ovarian response are proposed, including a more specific new definition of ‘‘low prognosis’’ patients.

314 citations

Journal ArticleDOI
David P. Schmitt1, Lidia Alcalay2, Melissa Allensworth1, Jüri Allik3, Lara Ault4, Ivars Austers5, Kevin Bennett6, Gabriel Bianchi7, Fredrick Boholst8, Mary Ann Borg Cunen9, Johan Braeckman10, Edwin G. Brainerd11, Leo Gerard A. Caral8, Gabrielle Caron, María Martina Casullo12, Michael Cunningham4, Ikuo Daibo13, Charlotte J. S. De Backer10, Eros De Souza14, Rolando Díaz-Loving15, Glaucia Ribeiro Starling Diniz16, Kevin Durkin17, Marcela Echegaray18, Ekin Eremsoy19, Harald A. Euler20, Ruth Falzon9, Maryanne L. Fisher21, Dolores Foley22, Robert Fowler1, Douglas P. Fry23, Sirpa Fry23, M. Arif Ghayur24, Vijai N. Giri25, Debra L. Golden26, Karl Grammer, Liria Grimaldi27, Jamin Halberstadt28, Shamsul Haque29, Dora Herrera18, Janine Hertel30, Amanda Hitchell1, Heather Hoffmann31, Danica Hooper22, Zuzana Hradilekova32, Jasna Hudek-Kene-Evi33, Allen I. Huffcutt1, Jas Laile Suzana Binti Jaafar34, Margarita Jankauskaite35, Heidi Kabangu-Stahel, Igor Kardum33, Brigitte Khoury36, Hayrran Kwon37, Kaia Laidra3, Anton Laireiter38, Dustin Lakerveld39, Ada Lampert, Mary Anne Lauri9, Marguerite Lavallée, Suk-Jae Lee40, Luk Chung Leung41, Kenneth D. Locke42, Vance Locke17, Ivan Lukšík7, Ishmael Magaisa43, Dalia Marcinkeviciene35, André Mata44, Rui Mata44, Barry Mccarthy45, Michael E. Mills46, Nhlanhla Mkhize47, João Manuel Moreira44, Sérgio Moreira44, Miguel Moya48, M. Munyae49, Patricia Noller22, Hmoud Olimat50, Adrian Opre51, Alexia Panayiotou52, Nebojša Petrović53, Karolien Poels10, Miroslav Popper7, Maria Poulimenou54, Volodymyr P'Yatokha, Michel Raymond55, Ulf-Dietrich Reips56, Susan E. Reneau57, Sofía Rivera-Aragón15, Wade C. Rowatt58, Willibald Ruch59, Velko S. Rus60, Marilyn P. Safir61, Sonia Salas62, Fabio Sambataro27, Kenneth Sandnabba23, Rachel Schleeter1, Marion K. Schulmeyer, Astrid Schütz30, Tullio Scrimali27, Todd K. Shackelford63, Mithila B. Sharan25, Phillip R. Shaver64, Francis J Sichona65, Franco Simonetti2, Tilahun Sineshaw66, R. Sookdew47, Tom Speelman10, Spyros Spyrou67, H. Canan Sümer, Nebi Sümer68, Marianna Supekova7, Tomasz Szlendak, Robin Taylor69, Bert Timmermans70, William Tooke71, Ioannis Tsaousis72, F. S.K. Tungaraza65, Ashley Turner1, Griet Vandermassen10, Tim Vanhoomissen73, Frank Van Overwalle73, Ine Vanwesenbeeck, Paul L. Vasey74, João Veríssimo44, Martin Voracek75, Wendy W.N. Wan76, Ta-Wei Wang77, Peter Weiss78, Andik Wijaya, Liesbeth Woertman39, Gahyun Youn79, Agata Zupanèiè60 
Bradley University1, Pontifical Catholic University of Chile2, University of Tartu3, University of Louisville4, University of Latvia5, University of New Mexico6, Slovak Academy of Sciences7, University of San Carlos8, University of Malta9, Ghent University10, Clemson University11, University of Buenos Aires12, Osaka University13, Illinois State University14, National Autonomous University of Mexico15, University of Brasília16, University of Western Australia17, University of Lima18, Boğaziçi University19, University of Kassel20, University of York21, University of Queensland22, Åbo Akademi University23, Al Akhawayn University24, Indian Institute of Technology Kharagpur25, University of Hawaii at Manoa26, University of Catania27, University of Otago28, University of Dhaka29, Chemnitz University of Technology30, Knox College31, Comenius University in Bratislava32, University of Rijeka33, University of Malaya34, Vilnius University35, American University of Beirut36, Kwangju Health College37, University of Salzburg38, Utrecht University39, National Computerization Agency40, City University of Hong Kong41, University of Idaho42, University of Zimbabwe43, University of Lisbon44, University of Central Lancashire45, Loyola Marymount University46, University of Natal47, University of Granada48, University of Botswana49, University of Jordan50, Babeș-Bolyai University51, University of Cyprus52, University of Belgrade53, KPMG54, University of Montpellier55, University of Zurich56, University of Alabama57, Baylor University58, Queen's University Belfast59, University of Ljubljana60, University of Haifa61, University of La Serena62, Florida Atlantic University63, University of California, Davis64, University of Dar es Salaam65, Ramapo College66, Cyprus College67, Middle East Technical University68, University of the South Pacific69, VU University Amsterdam70, State University of New York System71, University of the Aegean72, Vrije Universiteit Brussel73, University of Lethbridge74, University of Vienna75, University of Hong Kong76, Yuan Ze University77, Charles University in Prague78, Chonnam National University79
TL;DR: In the International Sexuality Description Project, a total of 17,804 participants from 62 cultural regions completed the RelationshipQuestionnaire (RQ), a self-report measure of adult romantic attachment as discussed by the authors.
Abstract: As part of the International Sexuality Description Project, a total of 17,804 participants from 62 cultural regions completedthe RelationshipQuestionnaire(RQ), a self-reportmeasure of adult romanticattachment. Correlational analyses within each culture suggested that the Model of Self and the Model of Other scales of the RQ were psychometrically valid within most cultures. Contrary to expectations, the Model of Self and Model of Other dimensions of the RQ did not underlie the four-category model of attachment in the same way across all cultures. Analyses of specific attachment styles revealed that secure romantic attachment was normative in 79% of cultures and that preoccupied romantic attachment was particularly prevalent in East Asian cultures. Finally, the romantic attachment profiles of individual nations were correlated with sociocultural indicators in ways that supported evolutionary theories of romantic attachment and basic human mating strategies.

314 citations


Authors

Showing all 14460 results

NameH-indexPapersCitations
D. M. Strom1763167194314
Christopher M. Dobson1501008105475
Dario Bisello1402005107859
Giorgio Maggi135132390270
Jörg P. Rachen13340094766
Pascal Vanlaer133127091850
Freya Blekman133138889808
Jorgen D'Hondt132125789685
Tae Jeong Kim132142093959
Xavier Janssen132130986860
Matthias Ulrich Mozer131118587709
Valery Zhukov129125583330
Stephanie Beauceron129121386374
Steven Lowette128109478876
Yen-Jie Lee128124782542
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023124
2022296
20212,413
20202,195
20192,169
20182,125