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Journal ArticleDOI

A systematic review of leukocyte telomere length and age in adults.

TLDR
While a decrease of LTL with age is out of question, data on variation of the decrease according to sex, age and other potential determinants especially from longitudinal data are still sparse.
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This article is published in Ageing Research Reviews.The article was published on 2013-03-01. It has received 382 citations till now.

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Citations
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Journal ArticleDOI

Lower anti-Müllerian hormone levels are associated with HIV in reproductive age women and shorter leukocyte telomere length among late reproductive age women

TL;DR: In this article , the authors examined cross-sectional and longitudinal associations between leukocyte telomere length (LTL), anti-Müllerian hormone (AMH), and HIV.
Journal ArticleDOI

Usefulness of Genetic Aberration and Shorter Telomere Length in Myelodysplastic Syndrome: A Pilot Study.

Hee Sue Park, +2 more
- 20 Sep 2022 - 
TL;DR: Genetic variation and shorter TL may be helpful in reclassifying non-high-risk groups and related to a poor long-term prognosis in individuals with myelodysplastic syndrome.
Journal ArticleDOI

Telomere length and chromosomal fragility increase in car painters exposed to organic solvents

TL;DR: In this paper , the authors evaluated the genotoxicity of exposure to organic solvents obtained the chromosomal fragility ratio and measuring the relative length of telomeres using qPCR (Cawthon's method).
Journal ArticleDOI

Linking Autism and Alzheimer’s: An integrated approach

TL;DR: The CT1812 being tested examines how proteins bind to the receptors involved in cell communication as mentioned in this paper, which has been shown to improve human memory in pre-clinical trials, according to Prof. Woodward SBS.
Posted ContentDOI

Detecting telomere elongation in longitudinal datasets: Analysis of a proposal by Simons, Stulp and Nakagawa

TL;DR: Power of the proposed test is likely to be low in several empirically-realistic scenarios, even in large samples, and type-II errors are a likely outcome, either if measurement error is substantial, and/or the true rate of attrition varies substantially over time within individuals.
References
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Journal ArticleDOI

Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method

TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
Journal ArticleDOI

Meta-analysis of observational studies in epidemiology - A proposal for reporting

TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

TL;DR: Development and application of REST is explained, the usefulness of relative expression in real-time PCR using REST is discussed and the mathematical model used is based on the PCR efficiencies and the mean crossing point deviation between the sample and control group.
Journal ArticleDOI

Telomeres shorten during ageing of human fibroblasts.

TL;DR: The amount and length of telomeric DNA in human fibroblasts does in fact decrease as a function of serial passage during ageing in vitro and possibly in vivo.

Van Damme A.

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