Journal ArticleDOI
A systematic review of leukocyte telomere length and age in adults.
TLDR
While a decrease of LTL with age is out of question, data on variation of the decrease according to sex, age and other potential determinants especially from longitudinal data are still sparse.About:
This article is published in Ageing Research Reviews.The article was published on 2013-03-01. It has received 382 citations till now.read more
Citations
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Journal ArticleDOI
Telomere length is longer in women with late maternal age.
Erin Fagan,Fangui Sun,Harold Bae,Irma T. Elo,Stacy L. Andersen,Joseph H. Lee,Kaare Christensen,Bharat Thyagarajan,Paola Sebastiani,Thomas T. Perls,Lawrence S. Honig,Nicole Schupf +11 more
TL;DR: Findings show an association between longer leukocyte telomere length and a later maternal age at birth of last child, suggesting that extended maternalAge at last childbirth may be a marker for longevity.
Journal ArticleDOI
Higher adherence to the ‘vegetable-rich’ dietary pattern is related to longer telomere length in women
TL;DR: Chinese women with higher adherence to 'vegetable-rich' dietary pattern have a longer telomere length, and this relation was partially explained by CRP but not by body fat.
Journal ArticleDOI
Caffeine consumption and telomere length in men and women of the National Health and Nutrition Examination Survey (NHANES)
TL;DR: Results suggest that caffeine consumption accounts for shorter telomeres in U.S. adults, independent of numerous covariates, whereas coffee intake predicts longer telomere length.
Journal ArticleDOI
Biological clocks and physical functioning in monozygotic female twins.
Elina Sillanpää,Elina Sillanpää,Eija K. Laakkonen,Elina Vaara,Taina Rantanen,Vuokko Kovanen,Sarianna Sipilä,Jaakko Kaprio,Miina Ollikainen +8 more
TL;DR: In this paper, the authors investigated if DNAm age and leukocyte telomere length (LTL) were associated with body composition and physical functioning by examining 48 monozygotic twin sisters.
Journal ArticleDOI
Telomere length analysis and preterm infant health: the importance of assay design in the search for novel biomarkers.
TL;DR: Analysis of telomere length maybe a plausible technique to predict prognosis in relation to preterm birth, and early life environmental and nutritional exposures and the tools available to measure telomeres are examined.
References
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Journal ArticleDOI
Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
Journal ArticleDOI
Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
TL;DR: Development and application of REST is explained, the usefulness of relative expression in real-time PCR using REST is discussed and the mathematical model used is based on the PCR efficiencies and the mean crossing point deviation between the sample and control group.
Journal ArticleDOI
Telomeres shorten during ageing of human fibroblasts.
TL;DR: The amount and length of telomeric DNA in human fibroblasts does in fact decrease as a function of serial passage during ageing in vitro and possibly in vivo.