Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
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Secondary structure, orientation, oligomerization, and lipid interactions of the transmembrane domain of influenza hemagglutinin.
Suren A. Tatulian,Lukas K. Tamm +1 more
TL;DR: The secondary structure, orientation, oligomerization, and lipid interactions of a synthetic peptide representing the transmembrane segment of X:31 HA (TMX31) by circular dichroism and attenuated total reflection Fourier transform infrared spectroscopy and by gel electrophoresis are studied.
Journal ArticleDOI
Exploring the conformational roles of signal sequences: synthesis and conformational analysis of lambda receptor protein wild-type and mutant signal peptides.
TL;DR: The helix content of the synthetic signal sequence fragments on the basis of CD measurements supports the secondary structure hypothesis described above, and the relative helicity in aqueous sodium dodecyl sulfate, lysolecithin, or trifluoroethanol is as follows.
Journal ArticleDOI
Deconvolution of the circular dichroism spectra of proteins: The circular dichroism spectra of the antiparallel β-sheet in proteins
TL;DR: The new pure component curves, which were obtained through deconvolution of the protein CD spectra alone, are promising candidates for determining the percentages of the secondary structural components in globular proteins without the necessity of adopting an X‐ray database.
Journal ArticleDOI
Conformational properties of four peptides spanning the sequence of hen lysozyme
Jenny J. Yang,Matthias Buck,Maureen Pitkeathly,Michael Kotik,Donald T. Haynie,Christopher M. Dobson,Sheena E. Radford +6 more
TL;DR: It is suggested that the region 84-129 could play an important role in determining the nature of the early folding events in the folding pathway of the intact polypeptide chain.
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Synthesis of redox derivatives of lysine and their use in solid-phase synthesis of a light-harvesting peptide
Dewey G. McCafferty,Barney Bishop,Craig G. Wall,Solon G. Hughes,Sandra L. Mecklenberg,Thomas J. Meyer,Bruce W. Erickson +6 more
TL;DR: In this article, the side chain e-amino group of Boc-l-lysine methyl ester or γ-carboxyl group was coupled to a redox moiety (transition-metal chromophore, electron donor, electron acceptor, metal ligand, or triplet-energy transmitter) using 4-(dimethylamino)pyridine, (1-benzotriazoleoxy)tris(dimethyamino)phosphonium hexafluorophosphate, N-methylmorpholine, and
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
Journal ArticleDOI
Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more