Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
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1H NMR spectroscopic studies of calcium-binding proteins. 3. Solution conformations of rat apo-alpha-parvalbumin and metal-bound rat alpha-parvalbumin.
Thomas C. Williams,David C. Corson,Kimio Oikawa,William D. McCubbin,Cyril M. Kay,Brian D. Sykes +5 more
TL;DR: In this paper, it was shown that at 25 degrees C, rat apo-alpha-parvalbumin unfolds entirely, losing the tertiary structure that characterizes its folded form: not only are the ring-current-shifted aromatic and methyl 1H NMR resonances leveled, but the 262 and 269-nm CD bands are also severely reduced.
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Circular dichroism study of the interaction of glutamyl-tRNA synthetase with tRNAGlu2.
Gordon E. Willick,Cyril M. Kay +1 more
TL;DR: The interaction of glutamyl-tRNA synthetase with tRNAGlu2 has been studied and results can be interpreted to indicate a change in the conformation of one or more of the helical regions of this molecule.
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The dimeric structure and the bivalent recognition of H3K4me3 by the tumor suppressor ING4 suggests a mechanism for enhanced targeting of the HBO1 complex to chromatin.
Alicia Palacios,Alberto Moreno,Bruno L. Oliveira,Teresa Rivera,Jesús Prieto,Pascal Garcia,M. Rosario Fernández-Fernández,Pau Bernadó,Ignacio Palmero,Francisco J. Blanco +9 more
TL;DR: Results show that ING4 is a bivalent reader of the chromatin H3K4me3 modification and suggest a mechanism for enhanced targeting of the HBO1 complex to specific chromatin sites, which could be common to other ING-containing remodeling complexes.
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The role of helix stabilizing residues in GCN4 basic region folding and DNA binding
TL;DR: The results suggest that the presence of Asp and Pro residues contributes significantly to helical structure and to the DNA‐binding ability of the basic region in the absence of the leucine zipper, and the implications for in vivo protein function are discussed.
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Characterization of the HIV N-terminal Fusion Peptide-containing Region in Context of Key gp41 Fusion Conformations
TL;DR: This study is the first to characterize the FP region in the context of the folded core and provides a basic understanding of the role of the elusive FP for key gp41 fusion conformations.
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
Journal ArticleDOI
Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
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Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more