Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
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Synthesis of a model protein of defined secondary and quaternary structure. Effect of chain length on the stabilization and formation of two-stranded alpha-helical coiled-coils.
TL;DR: In this paper, the ability of polyheptapeptides to form two-stranded alpha-helical coiled-coils in benign medium was monitored by molecular weight determinations and circular dichroism studies and their physical properties were compared to carboxamidomethylated alpha-tropomyosin at cysteine 190.
Journal ArticleDOI
Parameters of Helix-Coil Transition Theory for Alanine-Based Peptides of Varying Chain Lengths in Water *
TL;DR: The success of helix–coil theory in describing the unfolding transitions of short peptides in water indicates that helical propensities, or s values, can be determined from substitution experiments in short alanine‐based peptides.
Journal ArticleDOI
A structural model for maize zein proteins.
TL;DR: The polar, hydrophobic, and turn characteristics of the zein residues, as well as the homologous repeat units in their primary sequences, suggested a structure with nine adjacent, topologically antiparallel helices clustered within a distorted cylinder.
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Preferential heterodimer formation by isolated leucine zippers from fos and jun.
TL;DR: Peptides corresponding to leucine zipper regions from Fos and Jun correspond to autonomous helical dimerization sites that are likely to be short coiled coils, and these regions are sufficient to determine the specificity of interaction between Fo and Jun.
Journal ArticleDOI
Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1
Rogier W. Sanders,Mika Vesanen,Norbert Schuelke,Aditi Master,Linnea Schiffner,Roopa Kalyanaraman,Maciej Paluch,Ben Berkhout,Paul J. Maddon,William C. Olson,Min Lu,John P. Moore +11 more
TL;DR: The hypothesis is that a stable form of the Env complex, perhaps with additional modifications to rationally alter its antigenic structure, may be a better immunogen than the individual subunits.
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
Journal ArticleDOI
Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more