Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
Citations
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Journal ArticleDOI
A distinct 14 residue site triggers coiled‐coil formation in cortexillin I
Michel O. Steinmetz,Alexander Stock,Therese Schulthess,Ruth Landwehr,Ariel Lustig,Jan Faix,Günther Gerisch,Ueli Aebi,Richard A. Kammerer +8 more
TL;DR: Findings demonstrate that Arg311–Asp324 behaves as an autonomous helical folding unit and that this distinct Ir segment controls the process of coiled‐coil formation of cortexillin I.
Journal ArticleDOI
Metal ion induced conformational transitions of prothrombin and prothrombin fragment 1.
James W. Bloom,Kenneth G. Mann +1 more
TL;DR: Circular dichroism experiments show that caution must be used in interpreting the results of metal ion binding studies using fragment 1 as an analogue for prothrombin, as apparently only the fragment 1 portion of the molecule undergoes the transition.
Journal ArticleDOI
Human factor XII (Hageman factor) autoactivation by dextran sulfate. Circular dichroism, fluorescence, and ultraviolet difference spectroscopic studies.
TL;DR: Results indicate that DS500 (500-kDa dextran sulfate) induces aggregation of factor XII, and implies that aggregation provides a special mechanism whereby proteolytic cleavage is accomplished efficiently when factor XII molecules are bound side by side on the DS500 molecule.
Journal ArticleDOI
Molecular Studies on Bromovirus Capsid Protein
TL;DR: Northern blot analysis of virion RNAs and in vitro reassembly assays revealed that the N-terminal ARM region contains crucial amino acids required for RNA4 packaging, independent of genomic RNA3.
Journal ArticleDOI
The Conformation of Histone H5 Isolation and Characterisation of the Globular Segment
TL;DR: It is concluded that the resistant peptide, GH5, represents a globular folded region of the molecule whilst the rapidly digested parts are disordered and remains all the alpha-helical structure of intact H5 and appears to also maintain all the tertiary structure.
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
Journal ArticleDOI
Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more