Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
Citations
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Macromolecular crowding induces a molten globule state in the C-terminal domain of histone H1.
TL;DR: Native-like secondary structure and compactness in absence of folding cooperativity indicate that the C-terminus in crowding agents is in a molten globule state.
Journal ArticleDOI
Purification and characterization of potato lectin.
TL;DR: Equilibrium dialysis showed that STA (dimer) has two binding sites for a specific sugar per molecule, and the CD spectra of STA in the far UV region indicate the presence of 40% of beta- and 60% of unordered form, which supports the structure suggested by the amino acid composition and the high content of sugar.
Journal ArticleDOI
Biological characterization of a novel mammalian antimicrobial peptide
Renato Gennaro,Marco Scocchi,Marco Scocchi,Laura Merluzzi,Margherita Zanetti,Margherita Zanetti +5 more
TL;DR: A Western blot analysis using antibodies raised to the synthetic peptide showed that BMAP-34 is stored as proform in the cytoplasmic granules of bovine neutrophils, and CD spectroscopy indicates that the peptide assumes an amphipathic alpha-helical conformation, as predicted by secondary structure analysis.
Journal ArticleDOI
Comparison of helix stability in wild-type and mutant LamB signal sequences.
Martha D. Bruch,Lila M. Gierasch +1 more
TL;DR: It is found that the hydrophobic core has the most persistent helix conformation and that the stability of this helix correlates with in vivo function of different mutants of the LamB signal sequence.
Journal ArticleDOI
Biophysical property and broad anti-HIV activity of albuvirtide, a 3-maleimimidopropionic acid-modified peptide fusion inhibitor.
TL;DR: The results showed that ABT had potent inhibitory activity against the subtypes A, B and C that predominate the worldwide AIDS epidemics, and subtype B′, CRF07_BC and CRF01_AE recombinants that are currently circulating in China.
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
Journal ArticleDOI
Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more