Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
Citations
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Structural characterization of a partly folded apomyoglobin intermediate.
TL;DR: A structural model is presented for the partly folded intermediate of native myoglobin in which a compact subdomain retains structure while the remainder of the protein is essentially unfolded.
Journal ArticleDOI
Estimation of the number of alpha-helical and beta-strand segments in proteins using circular dichroism spectroscopy.
TL;DR: The method was used to analyze the circular dichroism spectra of four additional proteins and the predicted structural characteristics agree with the crystal structure data.
Journal ArticleDOI
Analyzing protein circular dichroism spectra for accurate secondary structures
TL;DR: An algorithm to analyze the circular dichroism of proteins for secondary structure is developed and a new basis set containing the CD spectra of 22 proteins with secondary structures from high quality X‐ray diffraction data is presented.
Journal ArticleDOI
SOAR and the polybasic STIM1 domains gate and regulate Orai channels
Joseph P. Yuan,Weizhong Zeng,Michael R. Dorwart,Young Jin Choi,Paul F. Worley,Shmuel Muallem +5 more
TL;DR: The characteristic inward rectification of Orai is mediated by an interaction between the polybasic STIM1 and a Pro-rich region in the N terminus of Obrai1 and the essential properties of ORAi1 function can be rationalized by interactions with discrete regions ofSTIM1.
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Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.
TL;DR: Findings suggest that nucleotide exchange on G proteins is regulated by the presentation of multiple cationic structures on the inner face of the plasma membrane.
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
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Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more