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Journal ArticleDOI

Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.

Yee-Hsiung Chen, +2 more
- 30 Jul 1974 - 
- Vol. 13, Iss: 16, pp 3350-3359
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.

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Purification and characterization of troponin C from pike muscle: a comparative spectroscopic study with rabbit skeletal muscle troponin C.

TL;DR: The results indicate near equivalence in many of the properties of pike and rabbit TN-C, such as molecular weight, the magnitude of the calcium-induced conformational change, and urea- or thermal-induced denaturability.
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Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion

TL;DR: It is concluded that negatively charged E3 acts as a “handle” for positively charged K3 and facilitates liposome docking, the first stage of the fusion process, through coiled-coil formation and the efficacy of this E3 handle is enhanced by longer spacer lengths.
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GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins

TL;DR: The development of a G: enetic A: l algorithm for D: esign of I: ntrinsic secondary S: tructure (GADIS) for designing sequences that satisfy the specified constraints of coupled folding and binding is reported.
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Isolation of domain-sized fragments of bovine serum albumin by limited peptic digestion and their secondary structural changes in solutions of urea, guanidine hydrochloride, and sodium dodecyl sulfate

TL;DR: In this article, three fragments of bovine serum albumin (BSA) by limited peptic hydrolysis were isolated and their positions in the parent molecule were identified on the basis of the analyses of plural amino acid residues at N- and C-terminals of each fragment.
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Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif.

TL;DR: The data provide a striking example of a naturally occurring amino sequence that exhibits context‐dependent folding into different oligomerization states, a three‐stranded versus a four-stranded coiled‐coil.
References