Journal ArticleDOI
Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.
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This article is published in Biochemistry.The article was published on 1974-07-30. It has received 1986 citations till now. The article focuses on the topics: Circular dichroism & Helix.read more
Citations
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Journal ArticleDOI
Elucidating the Folding Problem of Helical Peptides using Empirical Parameters. III>Temperature and pH Dependence
Victor Muñoz,Luis Serrano +1 more
TL;DR: In the accompanying paper the information about the conformational behaviour of helical peptides in solution, as well as the studies on alpha-helix stability in proteins has been utilised to derive a database of energy interactions, and the temperature and pH effects on the helical behaviour of peptides are included.
Journal ArticleDOI
The Unusually Stable Quaternary Structure of Human Cu,Zn-Superoxide Dismutase 1 Is Controlled by Both Metal Occupancy and Disulfide Status
Fabio Arnesano,Lucia Banci,Ivano Bertini,Manuele Martinelli,Yoshiaki Furukawa,Thomas V. O'Halloran +5 more
TL;DR: It is concluded that only the most immature form of hSOD1, i.e. one without any post-translational modifications, favors the monomeric state under physiological conditions, which provides a basis for understanding the selectivity of mitochondrial SOD1 import and may be relevant to the toxic properties of mutant forms of hO2 that can cause the familial form of amyotrophic lateral sclerosis.
Journal ArticleDOI
RNA recognition by an isolated α helix
TL;DR: The results suggest that interactions with the RNA backbone may help to orient the α helix in the major groove of RNA.
Journal ArticleDOI
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.
Richard A. Kahn,Paul A. Randazzo,T Serafini,O Weiss,C Rulka,Julia F. Clark,M Amherdt,Peter P. Roller,L Orci,James E. Rothman +9 more
TL;DR: It is concluded that ARF is required for the budding of coated vesicles from the Golgi stacks and serves a regulatory role in protein secretion through the Gol Gi in eukaryotic cells.
Book ChapterDOI
Lysozyme and alpha-lactalbumin: structure, function, and interrelationships.
TL;DR: This chapter considers both the structure and function of α-lactalbumin and lysozyme in relation to each other, and also the potential significance of the studies in health and the pathology of disease, such as cancer.
References
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Journal ArticleDOI
Computed circular dichroism spectra for the evaluation of protein conformation
Journal ArticleDOI
Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.
Journal ArticleDOI
Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.
C. C. F. Blake,D. F. Koenig,D. F. Koenig,G. A. Mair,A. C. T. North,D. C. Phillips,V. R. Sarma +6 more
TL;DR: Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 A Resolution as mentioned in this paper, 3D Fourier synthesis at 2 a resolution.
Journal ArticleDOI
Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution
J. C. Kendrew,R. E. Dickerson,B. E. Strandberg,R G Hart,D R Davies,D. C. Phillips,V. C. Shore +6 more