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Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures
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TLDR
In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.Abstract:
Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.read more
Citations
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Hydrogen‐bonded pseudopolyrotaxanes
Masumi Asakawa,Peter R. Ashton,Wayne Hayes,J. Fraser Stoddart,Brown George Robert,Stephan Menzer,Andrew J. P. White,David J. Williams +7 more
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Very-low energy vibrational modes as a fingerprint of H-bond network formation: L-Cysteine on Au(111)
TL;DR: In this paper, two vibrational modes, denoted as N and H modes, respectively, have been identified as distinguishing features of the homogeneous monolayer obtained at 330 K, where room-temperature deposition determined the formation of a quite heterogeneous first layer, where both weakly and strongly bound molecules coexist.
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Enzymatic self-assembly of nanostructures for theranostics.
Yue Chen,Gaolin Liang +1 more
TL;DR: The concept of enzymatic self-assembly is introduced and the design and application of enzyme-catalyzed or -regulated formation of nanostructures for theranostics is illustrated.
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Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging
Bo Dong,Shuangli Du,Chunxiao Wang,Haohao Fu,Qiang Li,Nannan Xiao,Jie Yang,Xue Xue,Wensheng Cai,Dingbin Liu +9 more
TL;DR: A robust reversible self-assembly system that is composed of a hydrophobic gold nanoparticle (AuNP) core and a shell of pH-responsive dye-incorporated block copolymers, supported by free-energy calculations to facilitate the study of pH influence on biological processes is described.
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Synthesis and characterization of designed BMHP1-derived self-assembling peptides for tissue engineering applications.
Diego Silva,Antonino Natalello,Babak Sanii,Rajesh Vasita,Gloria A. A. Saracino,Ronald N. Zuckermann,Silvia Maria Doglia,Fabrizio Gelain +7 more
TL;DR: Modifications in previously described BMHP1-derived SAPs were designed in order to investigate the influence of modified residues on self-assembly kinetics and scaffold formation properties, which demonstrated the potential of newly synthesized SAPs for regenerative medicine approaches.
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