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Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures
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TLDR
In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.Abstract:
Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.read more
Citations
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Journal ArticleDOI
Folding DNA to create nanoscale shapes and patterns
TL;DR: This work describes a simple method for folding long, single-stranded DNA molecules into arbitrary two-dimensional shapes, which can be programmed to bear complex patterns such as words and images on their surfaces.
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Fabrication of novel biomaterials through molecular self-assembly.
TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
Journal ArticleDOI
Design and self-assembly of two-dimensional DNA crystals
TL;DR: The design and observation of two-dimensional crystalline forms of DNA that self-assemble from synthetic DNA double-crossover molecules that create specific periodic patterns on the nanometre scale are reported.
Journal ArticleDOI
Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
TL;DR: This review is focused on current approaches emerging at the intersection of materials research, nanosciences, and molecular biotechnology, which is closely associated with both the physical and chemical properties of organic and inorganic nanoparticles.
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Self-assembly of DNA into nanoscale three-dimensional shapes
Shawn M. Douglas,Hendrik Dietz,Tim Liedl,Björn Högberg,Franziska Graf,Franziska Graf,William M. Shih,William M. Shih +7 more
TL;DR: This work demonstrates the design and assembly of nanostructures approximating six shapes—monolith, square nut, railed bridge, genie bottle, stacked cross, slotted cross, and heterotrimeric wireframe icosahedra with precisely controlled dimensions.
References
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Journal ArticleDOI
Molecular recognition among alcohols and amines: super-tetrahedral crystal architectures of linear diphenol–diamine complexes and aminophenols
Otto Ermer,Andreas Eling +1 more
TL;DR: In this article, it was shown that a 50% increase in the number of hydrogen-bond donors and acceptors is expected to lead to molecular recognition among alcohols and primary amines.
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Disruption of the Dynamics of Microtubules and Selective Inhibition of Glioblastoma Cells by Nanofibers of Small Hydrophobic Molecules
TL;DR: While the successful formation of supramolecular nanofibers of small molecules has resulted in hydrogels as a new class of biomaterials for tissue engineering,[6] drug delivery,[7] protein arrays,[8] electrophoresis,[9] bacteria typing,[10] and protocells, there is little exploration on the protein targets and cytotoxicity of the supramolescular nan ofibersOf small molecules.
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A Torsional Strain Mechanism To Tune Pitch in Supramolecular Helices
Liang-shi Li,Liang-shi Li,Hongzhou Jiang,Benjamin Weaver Messmore,Steve R. Bull,Samuel I. Stupp +5 more
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Cyclodextrin-covered organic nanotubes derived from self-assembly of dendrons and their supramolecular transformation
TL;DR: This work provides an efficient methodology not only to create an additional class of CD-covered organic nanotubes but also to exhibit reversible transformation of nanot tubes and vesicles triggered by the motifs of dendron self-assembly, CD inclusion, and pseudorotaxane formation.
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Instability, self-organization and pattern formation in thin soft films.
TL;DR: This article classify the instability of a thin polymer film into three broad categories, which are: instability of an ultra-thin (<100 nm) viscous film engendered by amplification of thermally excited surface capillary waves due to interfacial dispersive van der Waals forces, and instability arising from the attractive inter-surface interactions.