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Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures
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TLDR
In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.Abstract:
Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.read more
Citations
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Folding DNA to create nanoscale shapes and patterns
TL;DR: This work describes a simple method for folding long, single-stranded DNA molecules into arbitrary two-dimensional shapes, which can be programmed to bear complex patterns such as words and images on their surfaces.
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Fabrication of novel biomaterials through molecular self-assembly.
TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
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Design and self-assembly of two-dimensional DNA crystals
TL;DR: The design and observation of two-dimensional crystalline forms of DNA that self-assemble from synthetic DNA double-crossover molecules that create specific periodic patterns on the nanometre scale are reported.
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Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
TL;DR: This review is focused on current approaches emerging at the intersection of materials research, nanosciences, and molecular biotechnology, which is closely associated with both the physical and chemical properties of organic and inorganic nanoparticles.
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Self-assembly of DNA into nanoscale three-dimensional shapes
Shawn M. Douglas,Hendrik Dietz,Tim Liedl,Björn Högberg,Franziska Graf,Franziska Graf,William M. Shih,William M. Shih +7 more
TL;DR: This work demonstrates the design and assembly of nanostructures approximating six shapes—monolith, square nut, railed bridge, genie bottle, stacked cross, slotted cross, and heterotrimeric wireframe icosahedra with precisely controlled dimensions.
References
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Nanogap Field-Effect Transistor Biosensors for Electrical Detection of Avian Influenza
TL;DR: This work was supported by the National Research and Development Program for biomedical function-monitoring biosensor development, sponsored by the Korean Ministry of Education, Science and Technology, and by the MEST.
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Dynamic covalent chemistry of bisimines at the solid/liquid interface monitored by scanning tunnelling microscopy
Artur Ciesielski,Mohamed El Garah,Sébastien Haar,Petr Kovaříček,Jean-Marie Lehn,Paolo Samorì +5 more
TL;DR: It is shown that double imine formation between 4-(hexadecyloxy)benzaldehyde and different α,ω-diamines as well as reversible bistransimination reactions can be achieved at the solid/liquid interface, as monitored on the submolecular scale by in situ scanning tunnelling microscopy imaging.
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Impact of Regiochemistry and Isoelectronic Bridgehead Substitution on the Molecular Shape and Bulk Organization of Narrow Bandgap Chromophores
TL;DR: A comparison of two classes of small molecules relevant to the field of organic electronics is carried out at the molecular and supramolecular levels, demonstrating that the banana shape of the molecule can be controlled by replacing a Si atom within the dithienosilole fragment with a C or Ge atom.
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Pseudoknots: a new motif in the RNA game.
TL;DR: P pseudoknots are found to be a widespread structural motif in a number of functionally different RNAs involved in folding catalytic sites of ribozymes and can serve as specific binding sites for regulatory proteins.
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Toward the development of peptide nanofilaments and nanoropes as smart materials
Daniel E. Wagner,Charles L. Phillips,Wasif M. Ali,Grant E. Nybakken,Emily D. Crawford,Alexander D. Schwab,Walter F. Smith,Robert Fairman +7 more
TL;DR: The design and characterization of a helical peptide is shown, which uses phased hydrophobic interactions to drive assembly into nanofilaments and fibrils ("nanoropes") and circumvents problems of uncontrolled self-assembly seen in previous approaches that used electrostatics as a mode for self- assembly.