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Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures

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TLDR
In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.
Abstract
Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.

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Citations
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Folding DNA to create nanoscale shapes and patterns

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Fabrication of novel biomaterials through molecular self-assembly.

TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
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Design and self-assembly of two-dimensional DNA crystals

TL;DR: The design and observation of two-dimensional crystalline forms of DNA that self-assemble from synthetic DNA double-crossover molecules that create specific periodic patterns on the nanometre scale are reported.
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Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science

TL;DR: This review is focused on current approaches emerging at the intersection of materials research, nanosciences, and molecular biotechnology, which is closely associated with both the physical and chemical properties of organic and inorganic nanoparticles.
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Self-assembly of DNA into nanoscale three-dimensional shapes

TL;DR: This work demonstrates the design and assembly of nanostructures approximating six shapes—monolith, square nut, railed bridge, genie bottle, stacked cross, slotted cross, and heterotrimeric wireframe icosahedra with precisely controlled dimensions.
References
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Spontaneous assembly of viruses on multilayered polymer surfaces

TL;DR: It is demonstrated that this viral-assembled monolayer can be a biologically tunable scaffold to nucleate, grow and align nanoparticles or nanowires over multiple length scales and represents an interface that provides a general platform for the systematic incorporation and assembly of organic, biological and inorganic materials.
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Surface modification of polymers: chemical, biological and surface analytical challenges

TL;DR: Some of the chemical, surface analytical and biological challenges associated with surface modification of biosensors and biomedical devices are summarized.
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Designed synthesis of mesoporous solids via nonionic-surfactant-templating approach

TL;DR: Recent reports on the use of nonionic surfactant self-assembly as examples to fabricate high-quality ordered mesoporous solids which illustrates advances in synthesis and understanding of formation mechanisms are provided.
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Functional Dendrimers: Unique Biological Mimics

TL;DR: This article focuses on dendrimers in which the intriguing nature of the dendritic environment plays an active role in generating or controlling properties observed in biological systems, such as those illustrated.
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