Open Access
Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures
Reads0
Chats0
TLDR
In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.Abstract:
Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.read more
Citations
More filters
Journal ArticleDOI
Folding DNA to create nanoscale shapes and patterns
TL;DR: This work describes a simple method for folding long, single-stranded DNA molecules into arbitrary two-dimensional shapes, which can be programmed to bear complex patterns such as words and images on their surfaces.
Journal ArticleDOI
Fabrication of novel biomaterials through molecular self-assembly.
TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
Journal ArticleDOI
Design and self-assembly of two-dimensional DNA crystals
TL;DR: The design and observation of two-dimensional crystalline forms of DNA that self-assemble from synthetic DNA double-crossover molecules that create specific periodic patterns on the nanometre scale are reported.
Journal ArticleDOI
Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
TL;DR: This review is focused on current approaches emerging at the intersection of materials research, nanosciences, and molecular biotechnology, which is closely associated with both the physical and chemical properties of organic and inorganic nanoparticles.
Journal ArticleDOI
Self-assembly of DNA into nanoscale three-dimensional shapes
Shawn M. Douglas,Hendrik Dietz,Tim Liedl,Björn Högberg,Franziska Graf,Franziska Graf,William M. Shih,William M. Shih +7 more
TL;DR: This work demonstrates the design and assembly of nanostructures approximating six shapes—monolith, square nut, railed bridge, genie bottle, stacked cross, slotted cross, and heterotrimeric wireframe icosahedra with precisely controlled dimensions.
References
More filters
Journal ArticleDOI
Unusual ground states via monotonic convex pair potentials
TL;DR: This work adapts a linear programming method and applies it to optimize two repulsive monotonic convex pair potentials, whose classical ground states are counterintuitively the square and honeycomb crystals in R(2).
Journal ArticleDOI
Tools for the biomolecular engineer
TL;DR: Combined with protein bioengineering, molecular lithography provides a new, powerful tool for using DNA in future nanometer-scale devices.
Journal ArticleDOI
A Double Plug–Socket System Capable of Molecular Keypad Locks through Controllable Photooxidation
TL;DR: It was demonstrated that properly selected, rigid spacers are more efficient than flexible ones for achieving strong multivalent association and could be switched on and off by modulating their complexation through acid-base reactions, which is reminiscent of a plug-socket system capable of electron transfer.
Journal ArticleDOI
Promising avenues of research in nanoscience: chemistry of semiconductor nanoparticles
TL;DR: In this paper, the state-of-the-art in the field of research on semiconductor nanoparticles is analyzed; cadmium chalcogenide nanoparticles are considered in most detail.
Journal ArticleDOI
Characterization of nanofibers formed by self-assembly of β-peptide oligomers using small angle x-ray scattering
Claire L. Pizzey,William C. K. Pomerantz,Bong June Sung,Virany M. Yuwono,Samuel H. Gellman,Jeffery D. Hartgerink,Arun Yethiraj,Nicholas L. Abbott +7 more
TL;DR: Analysis of SAXS data suggests a model in which individual beta-peptides assemble to form long cylindrical nanofibers with a hollow core radius of 15 A (polydispersity of 21%) and a shell thickness of 20 A, supported by negative stain transmission electron microscopy.