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Molecular self-assembly and nanochemistry: A chemical strategy for the synthesis of nanostructures
TLDR
In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.Abstract:
Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.read more
Citations
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Synthesis and Self-Assembly of a Mikto-Arm Star Dual Drug Amphiphile Containing both Paclitaxel and Camptothecin
TL;DR: The hetero dual DA was found to effectively release the two anticancer agents, exhibiting superior cytotoxicity against PTX-resistant cervical cancer cells and provides the basis for a future combination therapy platform.
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Biomolecularly capped uniformly sized nanocrystalline materials: Glutathione-capped ZnS nanocrystals
Claudia L. Torres-Martínez,Liem Nguyen,Richard Kho,Weon Bae,Krassimir N. Bozhilov,Victor I. Klimov,Rajesh K. Mehra +6 more
TL;DR: In this article, the authors developed protocols for the synthesis of ZnS or CdS nanocrystals within a narrow size distribution range, which are characterized by optical spectroscopy, high-resolution transmission electron microscopy (HRTEM), x-ray diffraction and electron diffraction.
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Self-Assembly of Peptide-Based Colloids Containing Lipophilic Nanocrystals
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Lanthanide homobimetallic triple-stranded helicates: Insight into the self-assembly mechanism
TL;DR: In this paper, the self-assembly mechanism leading to the exclusive formation of a triple-stranded bimetallic helicate upon reaction of Eu III with a ditopic hexadentate ligand L bearing two carboxylate moieties has been fully elucidated in water for a wide range of [Eu]tot/[L]to ratios.
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Hierarchical structure and polymorphism of a sphere-cubic shape amphiphile based on a polyhedral oligomeric silsesquioxane–[60]fullerene conjugate
Hao-Jan Sun,Yingfeng Tu,Chien-Lung Wang,Ryan M. Van Horn,Chi-Chun Tsai,Matthew J. Graham,Bin Sun,Bernard Lotz,Wen-Bin Zhang,Stephen Z. D. Cheng +9 more
TL;DR: A shape amphiphile composed of covalently linked spherical and cubic nanoparticles with distinct symmetry (60]fullerene (C60) and polyhedral oligomeric silsesquioxane (POSS)) was synthesized and its solid state structures were characterized as mentioned in this paper.
References
More filters
Journal ArticleDOI
Folding DNA to create nanoscale shapes and patterns
TL;DR: This work describes a simple method for folding long, single-stranded DNA molecules into arbitrary two-dimensional shapes, which can be programmed to bear complex patterns such as words and images on their surfaces.
Journal ArticleDOI
The nature of .pi.-.pi. interactions
Journal ArticleDOI
Encoding and decoding hydrogen-bond patterns of organic compounds
Journal ArticleDOI
Fabrication of novel biomaterials through molecular self-assembly.
TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
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Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices (Nobel Lecture)
TL;DR: Developments in molecular and supramolecular design and engineering open perspectives towards the realization of molecular photonic, electronic, and ionic devices that would perform highly selective recognition, reaction, and transfer operations for signal and information processing at the molecular level.