REBASE—a database for DNA restriction and modification: enzymes, genes and genomes
TLDR
REBASE is a comprehensive and fully curated database of information about the components of restriction-modification (RM) systems that contains fully referenced information about recognition and cleavage sites for both restriction enzymes and methyltransferases as well as commercial availability, methylation sensitivity, crystal and sequence data.Abstract:
REBASE is a comprehensive and fully curated database of information about the components of restriction-modification (RM) systems. It contains fully referenced information about recognition and cleavage sites for both restriction enzymes and methyltransferases as well as commercial availability, methylation sensitivity, crystal and sequence data. All genomes that are completely sequenced are analyzed for RM system components, and with the advent of PacBio sequencing, the recognition sequences of DNA methyltransferases (MTases) are appearing rapidly. Thus, Type I and Type III systems can now be characterized in terms of recognition specificity merely by DNA sequencing. The contents of REBASE may be browsed from the web http://rebase.neb.com and selected compilations can be downloaded by FTP (ftp.neb.com). Monthly updates are also available via email.read more
Citations
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Woronichinia naegeliana: A common nontoxigenic component of temperate freshwater cyanobacterial blooms with 30% of its genome in transposons.
TL;DR: The first complete genome of W. naegeliana WA131, assembled from the metagenome of a sample collected from Wiser Lake, Washington, in 2018, was reported in this paper .
Journal ArticleDOI
Complete Genome Sequencing Analysis of Deinococcus wulumuqiensis R12, an Extremely Radiation-Resistant Strain
TL;DR: The comprehensive description of the genome of R12 will facilitate the additional exploitation of this strain as a versatile cell factory for biotechnological applications and help develop endogenous CRISPR-Cas gene-editing tools.
Posted ContentDOI
Integration of the Salmonella Typhimurium methylome and transcriptome following environmental or metabolic perturbation reveals DNA methylation and transcriptional regulation are largely decoupled
Jeffrey S. Bourgeois,Caroline E. Anderson,Liuyang Wang,Jennifer L. Modliszewski,Wei Chen,Benjamin Schott,Nicolas Devos,Dennis C. Ko +7 more
TL;DR: In this paper, the m6A DNA methylome of two Salmonella enterica ser. Typhimurium strains was examined using SMRT sequencing to examine the plasticity and functional impacts of the bacterial DNA epigenome.
Posted ContentDOI
Long-read sequencing reveals extensive DNA methylations in human gut phagenome contributed by prevalently phage-encoded methyltransferases
Chuqing Sun,Jingchao Chen,Menglu Jin,Xueyang Zhao,Yun Yvonna Li,Yanqi Dong,Na L Gao,Zhi Liu,Peer Bork,Xing-Ming Zhao,Weihua Chen +10 more
TL;DR: In this paper , the DNA methylation patterns of 8,848 metagenome-assembled high-quality phages across 104 fecal samples using single-molecule real-time (SMRT) sequencing were analyzed.
ASOCIACIÓN ENTRE LA ALTERACIÓN DEL METABOLISMO DE LA HOMOCISTEÍNA- METIONINA Y FOLATO, Y EL RETARDO DE CRECIMIENTO INTRAUTERINO IDIOPÁTICO (RCIU). DATOS PRELIMINARES The association between homocysteine-methionine and folate metabolism and pregnancy complicated by idiopathic intrauterine growth restriction - Preliminary data
Reggie García-Robles,Catalina Durán-Garzón,Paola Ayala-Ramírez,Rodolfo Martínez-Díaz,Martha Bermúdez de Rincón,Jaime Bernal-Villegas +5 more
TL;DR: The association between homocysteine-methionine and folate metabolism and pregnancy complicated by idiopathic intrauterine growth restriction and preliminary data are released.
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