REBASE—a database for DNA restriction and modification: enzymes, genes and genomes
TLDR
REBASE is a comprehensive and fully curated database of information about the components of restriction-modification (RM) systems that contains fully referenced information about recognition and cleavage sites for both restriction enzymes and methyltransferases as well as commercial availability, methylation sensitivity, crystal and sequence data.Abstract:
REBASE is a comprehensive and fully curated database of information about the components of restriction-modification (RM) systems. It contains fully referenced information about recognition and cleavage sites for both restriction enzymes and methyltransferases as well as commercial availability, methylation sensitivity, crystal and sequence data. All genomes that are completely sequenced are analyzed for RM system components, and with the advent of PacBio sequencing, the recognition sequences of DNA methyltransferases (MTases) are appearing rapidly. Thus, Type I and Type III systems can now be characterized in terms of recognition specificity merely by DNA sequencing. The contents of REBASE may be browsed from the web http://rebase.neb.com and selected compilations can be downloaded by FTP (ftp.neb.com). Monthly updates are also available via email.read more
Citations
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Journal ArticleDOI
MicroRNA Expression Profiling of the Armed Forces Health Surveillance Branch Cohort for Identification of "Enviro-miRs" Associated With Deployment-Based Environmental Exposure.
Clifton L. Dalgard,Keith F. Polston,Gauthaman Sukumar,Col Timothy M. Mallon,Matthew D. Wilkerson,Harvey B. Pollard +5 more
TL;DR: Serum miRNAs are candidate biomarkers for deployment and environmental exposure in military service members and are suitable RNA species for biomarker discovery in the DoDSR serum specimens.
Computational genomics of lactobacilli
TL;DR: In this paper, the authors present a list of original publications 3.1.1! List of original publication 3.3.1, and 3.4.1...
Journal ArticleDOI
The Effect of Iodine-Containing Nano-Micelles, FS-1, on Antibiotic Resistance, Gene Expression and Epigenetic Modifications in the Genome of Multidrug Resistant MRSA Strain Staphylococcus aureus ATCC BAA-39
Oleg N. Reva,Ilya S. Korotetskiy,Monique Joubert,Sergey V. Shilov,Ardak B. Jumagaziyeva,Natalya A. Suldina,Alexandr I. Ilin +6 more
TL;DR: The selection against the antibiotic resistance in bacterial populations caused by abnormal epigenetic modifications exemplifies possible mechanisms of antibiotic resistance reversion induced by iodine-containing compounds.
Dissertation
Clonage et modification du génome de Mycoplasma hominis dans la levure Saccharomyces cerevisiae
TL;DR: De nouvelles technologies rassemblees sous le terme de Biologie de Synthese (BS) ont recemment emerge, offrant des perspectives inedites pour l’etude des mycoplasmes en permettant de modifier leurs genomes a grande echelle et de produire des souches mutantes.
Patent
Optimized vector for delivery in microbial populations
TL;DR: In this paper, a vector, preferably included in a delivery vehicle, comprising no more than 100 restriction sites recognized by the restriction enzymes encoded by each bacterium of a group of interest.
References
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