Journal ArticleDOI
Sleep function and synaptic homeostasis.
Giulio Tononi,Chiara Cirelli +1 more
TLDR
This paper reviews a novel hypothesis about the functions of slow wave sleep-the synaptic homeostasis hypothesis, which accounts for a large number of experimental facts, makes several specific predictions, and has implications for both sleep and mood disorders.About:
This article is published in Sleep Medicine Reviews.The article was published on 2006-02-01. It has received 1864 citations till now. The article focuses on the topics: Synaptic scaling & Sleep and memory.read more
Citations
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Dissertation
Learning new words: effects of meaning, memory consolidation, and sleep
TL;DR: This paper investigated the role of sleep in the consolidation of novel words and found that sleep spindles are associated with lexical competition effects, suggesting that sleep has an active role in word learning.
Journal ArticleDOI
Electrophysiological correlates of sleep disturbance induced by acute and chronic administration of D-amphetamine.
Monica L. Andersen,Regina Margis,Benicio N. Frey,Larriany Maria Falsin Giglio,Flávio Kapczinski,Sergio Tufik +5 more
TL;DR: It is suggested that AMPH produces profound sleep disturbances and decreases PS sleep, and both acute and chronic AMPH administration induced longer latencies to both slow wave sleep and paradoxical sleep.
BookDOI
Neuronal Network Analysis
TL;DR: Some of the currently available optical methods are discussed while highlighting their relative strengths and weaknesses, to help understand neural circuits with unprecedented detail and specificity.
Journal ArticleDOI
Motive Control of Unconscious Inference: The Limbic Base of Adaptive Bayes.
Don M. Tucker,Phan Luu +1 more
TL;DR: In this article, the adaptive Bayes process model is proposed to organize the operations of predictive coding across the multiple levels of the neocortex. But the model does not address the problem of how limbic cortex resonates to the homeostatic, personal significance of events.
References
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Book
Psychopharmacology: The Fourth Generation of Progress
Floyd E. Bloom,David J. Kupfer +1 more
TL;DR: Part 1 Preclinical section: critical analysis of methods transmitter systems - amino acids, amines, peptides, new transmitterscritical analysis of integrative concepts.
Journal ArticleDOI
An Energy Budget for Signaling in the Grey Matter of the Brain
David Attwell,Simon B. Laughlin +1 more
TL;DR: The estimates of energy usage predict the use of distributed codes, with ≤15% of neurons simultaneously active, to reduce energy consumption and allow greater computing power from a fixed number of neurons.
Journal ArticleDOI
Regional differences in synaptogenesis in human cerebral cortex.
TL;DR: Findings in the human resemble those in rhesus monkeys, including overproduction of synaptic contacts in infancy, persistence of high levels of synaptic density to late childhood or adolescence, the absolute values of maximum and adult synaptic density, and layer specific differences.
Journal ArticleDOI
The Cumulative Cost of Additional Wakefulness: Dose-Response Effects on Neurobehavioral Functions and Sleep Physiology From Chronic Sleep Restriction and Total Sleep Deprivation
TL;DR: It appears that even relatively moderate sleep restriction can seriously impair waking neurobehavioral functions in healthy adults, and sleep debt is perhaps best understood as resulting in additional wakefulness that has a neurobiological "cost" which accumulates over time.
Journal ArticleDOI
Reactivation of hippocampal ensemble memories during sleep.
TL;DR: In this paper, large ensembles of hippocampal "place cells" were recorded from three rats during spatial behavioral tasks and in slow-wave sleep preceding and following these behaviors, showing an increased tendency to fire together during subsequent sleep, in comparison to sleep episodes preceding the behavioral tasks.