Journal ArticleDOI
Sleep function and synaptic homeostasis.
Giulio Tononi,Chiara Cirelli +1 more
TLDR
This paper reviews a novel hypothesis about the functions of slow wave sleep-the synaptic homeostasis hypothesis, which accounts for a large number of experimental facts, makes several specific predictions, and has implications for both sleep and mood disorders.About:
This article is published in Sleep Medicine Reviews.The article was published on 2006-02-01. It has received 1864 citations till now. The article focuses on the topics: Synaptic scaling & Sleep and memory.read more
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Book
Rhythms of the brain
TL;DR: The brain's default state: self-organized oscillations in rest and sleep, and perturbation of the default patterns by experience.
Journal ArticleDOI
The memory function of sleep
Susanne Diekelmann,Jan Born +1 more
TL;DR: Sleep has been identified as a state that optimizes the consolidation of newly acquired information in memory, depending on the specific conditions of learning and the timing of sleep, through specific patterns of neuromodulatory activity and electric field potential oscillations.
Journal ArticleDOI
About sleep's role in memory
Bjoern Rasch,Jan Born,Jan Born +2 more
TL;DR: This review aims to comprehensively cover the field of "sleep and memory" research by providing a historical perspective on concepts and a discussion of more recent key findings.
Journal ArticleDOI
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition
TL;DR: A plethora of studies will be reviewed on the involvement of long-distance neuronal coherence in cognitive functions such as multisensory integration, working memory, and selective attention, and implications of abnormal neural synchronization are discussed as they relate to mental disorders like schizophrenia and autism.
Journal ArticleDOI
Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms
TL;DR: Greater appreciation of the convergence of mechanisms between stress, depression, and neuroplasticity is likely to lead to the identification of novel targets for more efficacious treatments.
References
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Journal ArticleDOI
A neuronal group theory of sleep function
James M. Krueger,Ferenc Obäl +1 more
TL;DR: A new theory of sleep function is presented within the context of the neuronal group selection hypothesis, which emphasizes that neuronal groups compete for neurons via use‐dependent synaptic formation and atrophy.
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The ventral striatum in off-line processing: Ensemble reactivation during sleep and modulation by hippocampal ripples
Cyriel M. A. Pennartz,Eunjeong Lee,J. Verheul,Peter Lipa,Carol A. Barnes,Bruce L. McNaughton +5 more
TL;DR: The data suggest, first, the occurrence of pattern replay in a subcortical structure implied in the processing and prediction of reward and, second, a functional linkage between ventral striatal reactivation and a specific type of high-frequency population activity associated with hippocampal replay.
Journal ArticleDOI
Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: empirical data and simulations
TL;DR: The capacity of the model to predict SWA in nonREM sleep on the basis of the temporal organization of sleep in mice was tested and provided a basis for the use of gene targeted mice to investigate the underlying mechanisms.
Journal ArticleDOI
Molecular and cellular cognitive studies of the role of synaptic plasticity in memory
TL;DR: In the last decade, mouse transgenetics have provided compelling evidence that the molecular mechanisms responsible for the induction and stability of synaptic changes have a critical role in the acquisition and storage of information.
Journal ArticleDOI
Insomnia causes, consequences, and therapeutics: an overview.
TL;DR: This theoretical overview of insomnia describes the negative impact, etiological considerations, and pharmacological and behavioral treatments for the disorder, with an emphasis on areas receiving increased research attention.