Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
About:
This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
Citations
More filters
Journal ArticleDOI
Development of dual scale scaffolds via direct polymer melt deposition and electrospinning for applications in tissue regeneration.
TL;DR: The results showed that the polymeric scaffolds with nanofiber matrices fabricated using the proposed hybrid process provided favorable conditions for cell adhesion and proliferation.
Journal ArticleDOI
An electrochemical fabrication process for the assembly of anisotropically oriented collagen bundles.
Xingguo Cheng,Umut A. Gurkan,Christopher J. Dehen,Michael P. Tate,Hugh W. Hillhouse,Garth J. Simpson,Ozan Akkus +6 more
TL;DR: Results indicate that the electrochemically oriented collagen scaffolds carry baseline characteristics to be considered for tendon/ligament repair and the anisotropic order within biocompatible collagenous constructs was conferred upon the nuclear morphology of cells as well.
Journal ArticleDOI
Nanostructured polymer scaffolds for tissue engineering and regenerative medicine
TL;DR: A novel thermally induced phase separation process in which a solution of biodegradable polymer is cast into a porous scaffold, resulting in a nanofibrous pore-wall structure that showed a decrease in incidence of apoptosis when compared to polymer control in bone tissue engineering.
Journal ArticleDOI
Tissue engineering of a bioartificial renal tubule assist device: In vitro transport and metabolic characteristics
TL;DR: This device, when placed in series with conventional hemofiltration therapy, may provide incremental renal replacement support and potentially may decrease the high morbidity and mortality rates observed in patients with renal failure.
Journal ArticleDOI
Injectable biodegradable hydrogels: progress and challenges
TL;DR: An overview of state-of-the-art strategies towards constructing a rational design of injectable biodegradable hydrogels for protein drug delivery and tissue engineering is provided.