Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Human foetal osteoblastic cell response to polymer-demixed nanotopographic interfaces
TL;DR: Modulation of nanoscale topography may be exploited to control cell function at cell–biomaterial interfaces and not only affect adhesion-related cell behaviour but also bone cell phenotype.
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Release from alginate enhances the biological activity of vascular endothelial growth factor.
TL;DR: The released VEGF, when assayed for its ability to stimulate endothelial cells in culture, was found not only to be functional but more potent than the same mass of V EGF added directly to the culture medium.
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Covalent immobilization of chitosan/heparin complex with a photosensitive hetero-bifunctional crosslinking reagent on PLA surface.
TL;DR: Platelet adhesion assay showed that PLA surface modified by chitosan/heparin complex could inhibit platelets adhesion and activation, and cell culture assay indicated thatPLA surface with CS/Hp complex showed enhanced cell adhesion.
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Collagen fabrics as biomaterials.
TL;DR: Braids and bundles of collagen threads implanted as a replacement of the anterior cruciate ligament in a dog model were completely remodeled into host tissue by 12 weeks, and knit collagen fabrics implanted in a rat abdominal repair model prevented herniation, and connective tissue ingrowth was observed within the fabric.