Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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PCL microspheres based functional scaffolds by bottom-up approach with predefined microstructural properties and release profiles.
Alessia Luciani,Valentina Coccoli,Valentina Coccoli,Silvia Orsi,Silvia Orsi,Luigi Ambrosio,Paolo A. Netti,Paolo A. Netti +7 more
TL;DR: A bottom-up approach for the realization of bioactive scaffolds with controllable pore size and interconnection, combined with protein-loaded polymeric microcarriers acting as local chrono-programmed point source generation of bio active signals is proposed.
Journal ArticleDOI
Investigation of cell-surface interactions using chemical gradients formed from plasma polymers.
Mischa Zelzer,Ruby Majani,James W. Bradley,Felicity R. A. J. Rose,Martyn C. Davies,Morgan R. Alexander +5 more
TL;DR: This paper reports on the application of surface chemical gradients to study mammalian cell interactions with synthetic surfaces and investigates if the cell response on certain parts of the gradient is the same as that on uniform surfaces of equivalent chemistry.
Journal ArticleDOI
Translational research for injectable tissue-engineered bone regeneration using mesenchymal stem cells and platelet-rich plasma: from basic research to clinical case study.
TL;DR: This investigation investigated tissue-engineered bone regeneration using mesenchymal stem cells and platelet-rich plasma and regenerated bone with minimal invasiveness and good plasticity, which could provide a clinical alternative to autogenous bone grafts.
Book ChapterDOI
Chitosan-Based Biomaterials for Tissue Repair and Regeneration
TL;DR: Chitosan is a natural polysaccharide exhibiting excellent biocompatibility, biodegradability, affinity to biomolecules, and wound-healing activity.
Journal ArticleDOI
Preliminary results of small arterial substitute performed with a new cylindrical biomaterial composed of bacterial cellulose.
TL;DR: Data indicate that the innovative BC-engineering technique results in the production of stable vascular conduits, which exhibit attractive properties for their use in future TEBV programmes for vascular surgery.