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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
- Vol. 260, Iss: 5110, pp 920-926
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.

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Synthetic biodegradable functional polymers for tissue engineering: a brief review

TL;DR: The scaffold designs that mimic the nano and micro features of the extracellular matrix (ECM) are presented as well, and composite and nanocomposite scaffolds are also reviewed.
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3D printing of hydrogels: Rational design strategies and emerging biomedical applications

TL;DR: A review of hydrogel-based biomaterial inks and bioinks for 3D printing can be found in this paper, where the authors provide a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties.
Journal ArticleDOI

Engineering growing tissues

TL;DR: It is hypothesized that tissues capable of growing with time could be engineered by supplying growth stimulus signals to cells from the biomaterial used for cell transplantation, and this concept of promoting the growth of engineered tissues could find great utility in engineering numerous tissue types by way of the transplantation of a small number of precursor cells.
Journal ArticleDOI

Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments

TL;DR: In this paper, the use of different types of polymeric matrix composites in hard tissue replacement applications is examined.The review presents the actual state of the art in the fields of bioinert composites for permanent applications, biodegradable matrix composite for temporary applications and the emerging area of injectable composites.
Journal ArticleDOI

Fundamentals of double network hydrogels

TL;DR: This review strives to highlight the development and fundamentals of DN gels covering from preparation methods, network structures, to toughening mechanisms over the last decade to derive new design principles for the next-generation tough hydrogels.
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