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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
- Vol. 260, Iss: 5110, pp 920-926
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.

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Heart muscle engineering: An update on cardiac muscle replacement therapy

TL;DR: An update on the state of cardiac muscle engineering and its utilization in cardiac regeneration is provided and the application of stem cells including the allocation of autologous cell material, transgenic technologies that may improve tissue structure as well as in vivo engraftment, and vascularization concepts are discussed.
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Toward Strong and Tough Glass and Ceramic Scaffolds for Bone Repair

TL;DR: Inspired by the designs of natural materials such as cortical bone and nacre, glass‐ceramic and inorganic/polymer composite scaffolds created with extrinsic toughening mechanisms are showing potential for both high strength and mechanical reliability.
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Supercritical fluids processing of polymers for pharmaceutical and medical applications

TL;DR: A critical analysis of the supercritical fluids based technologies that have been proposed in polymer processing for pharmaceutical and medical applications is presented in this article, where the formation of polymer-drug microparticles and microspheres, the production of simple or loaded membranes and formation of temporary scaffolds are reviewed and the future trends in these areas are analyzed.
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Studies on nerve cell affinity of chitosan-derived materials.

TL;DR: It is found that both CAP and CPL have excellent nerve cell affinity, defined as the ability to promote nerve cell to grow and function normally, and those two materials may be promising for the repair of the nervous system.
Journal ArticleDOI

Supercritical Fluid Technology: An Emphasis on Drug Delivery and Related Biomedical Applications.

TL;DR: Recent advances in drug delivery systems manufactured using the SCF technology are reviewed and an emphasis and discussion of recent reports using supercritical carbon dioxide (SC‐CO2) for fabrication of polymeric carriers for applications in areas related to drug delivery, tissue engineering, bio‐imaging, and other biomedical applications are provided.
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