Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Matrices and scaffolds for protein delivery in tissue engineering.
Joerg Tessmar,Achim Göpferich +1 more
TL;DR: To illustrate the enormous progress that has been achieved in the important field of controlled release, some of the recently developed cell carriers with controlled release capacity, including both solid scaffolds and hydrogel-derived scaffolds are described and possible solutions for unresolved issues are illustrated.
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Microfabrication and microfluidics for tissue engineering : state of the art and future opportunities
TL;DR: It is concluded that until today, microfluidic devices have not been used extensively in tissue engineering, and major contributions are expected in two areas: growth of complex tissue, and the development of in vitro physiological systems for studying fundamental biological phenomena.
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Integration of surface modification and 3D fabrication techniques to prepare patterned poly(L-lactide) substrates allowing regionally selective cell adhesion.
TL;DR: The approach may be generally useful for creating regionally selective, microarchitectured scaffolds fabricated from biodegradable polymers, for spatial organization of diverse cell types.
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Collagen-chitosan polymeric scaffolds for the in vitro culture of human epidermoid carcinoma cells.
N Shanmugasundaram,N Shanmugasundaram,P Ravichandran,P. Neelakanta Reddy,Nalini Ramamurty,Subrata Pal,K. Panduranga Rao +6 more
TL;DR: The results of the above studies suggest that the scaffolds prepared from collagen and chitosan can be utilized as a substrate to culture HEp-2 cells and can also be used as an in vitro model to test anticancerous drugs.
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Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system.
Xiawei Wei,Changyang Gong,Maling Gou,ShaoZhi Fu,QingFa Guo,Shuai Shi,Feng Luo,Gang Guo,Liyan Qiu,Zhiyong Qian +9 more
TL;DR: Several aspects of PCL-PEG copolymers are introduced, including synthetic chemistry, PCL -PEG micro/nanoparticles,PCL- PEG hydrogels, and physicochemical and toxicological properties.