Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Preparation and characterization of RGD-immobilized chitosan scaffolds
Ming-Hua Ho,Da-Ming Wang,Hsyue-Jen Hsieh,Hwa-Chang Liu,Tzu-Yang Hsien,Juin-Yih Lai,Lein-Tuan Hou +6 more
TL;DR: The results presented in this work suggest that immobilization of RGDS can make chitosan scaffolds more compatible for the culture of osteoblast-like cells and the regeneration of bone-like tissues.
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Differential regulation of osteogenic differentiation of stem cells on surface roughness gradients.
Ana B. Faia-Torres,Stefanie Guimond-Lischer,Markus Rottmar,Mirren Charnley,Tolga Goren,Katharina Maniura-Weber,Nicholas D. Spencer,Rui L. Reis,Marcus Textor,Nuno M. Neves +9 more
TL;DR: The stem-cell modulation by specific PCL roughness surfaces highlights the potential for creating effective solutions for orthopedic applications featuring a clinically relevant biodegradable material.
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Advances in tissue engineering of blood vessels and other tissues
Laura E. Niklason,Robert Langer +1 more
TL;DR: Preliminary studies have achieved good cell densities of both smooth muscle cells and endothelial cells on biodegradable polymer scaffolds, which holds the potential for the in vitro development of autologous or allogeneic transplantable vascular conduits.
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Characterization of thermoplastic polyurethane/polylactic acid (TPU/PLA) tissue engineering scaffolds fabricated by microcellular injection molding
Hao-Yang Mi,Max R. Salick,Xin Jing,Xin Jing,Brianna R. Jacques,Wendy C. Crone,Xiangfang Peng,Lih-Sheng Turng +7 more
TL;DR: This study demonstrated the feasibility of mass producing biocompatible PLA/TPU scaffolds with tunable microstructures, surface roughnesses, and mechanical properties that have the potential to be used as artificial scaffolds in multiple tissue engineering applications.
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Tendon tissue engineering using scaffold enhancing strategies.
TL;DR: A variety of specialized methodologies have been developed or adopted to enhance neo-tendogenesis, including cellular hybridization, interfacing improvement, and physical stimulation.