Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Compositional effects on the formation of a calcium phosphate layer and the response of osteoblast-like cells on polymer-bioactive glass composites.
TL;DR: The results of this study suggest that there is a threshold BG content which is optimal for osteoblast growth, and the interactions between PLAGA and BG may modulate the kinetics of Ca-P formation and the overall cellular response.
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Evolving insights in cell-matrix interactions: elucidating how non-soluble properties of the extracellular niche direct stem cell fate.
Nick J. Walters,Eileen Gentleman +1 more
TL;DR: How insights from 2-D biomaterials are being used to examine cellular behaviours in more complex 3-D hydrogel systems, in which not only matrix stiffness, but also degradability, plays an important role, and in which defining the nanoscale ligand presentation presents an additional challenge is discussed.
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Recent advances in periodontal regeneration: A biomaterial perspective.
TL;DR: Recent progresses of periodontal regeneration using tissue-engineering and regenerative medicine approaches are discussed, with special attention given to the development of advanced bio-inspired scaffolding biomaterials and temporospatial control of multi-drug delivery for the regeneration of cementum-periodontal ligament-alveolar bone complex.
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Nanoscale engineering of extracellular matrix-mimetic bioadhesive surfaces and implants for tissue engineering.
Asha Shekaran,Andrés J. García +1 more
TL;DR: Combining bioadhesion and nanopatterning technologies to allow nanoscale control of adhesive motifs on the cell-material interface may result in exciting advances in tissue engineering.
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Platelet-Derived Growth Factor (PDGF) Gene Delivery for Application in Periodontal Tissue Engineering
TL;DR: These findings demonstrate that gene delivery of platelet-derived growth factor stimulates cementoblast activity that is sustained above that of rhPDGF-AA application and offers a novel approach to periodontal tissue engineering.