Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Surface Engineered Polymeric Biomaterials with Improved Biocontact Properties
TL;DR: Many examples of surface engineered polymeric biomaterials with nanosize modified layers, controlled protein adsorption, and cellular interactions potentially applicable for tissue and/or blood contacting devices, scaffolds for cell culture and tissue engineering, biosensors, biological microchips as well as approaches to their preparation are presented.
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Should we use cells, biomaterials, or tissue engineering for cartilage regeneration?
TL;DR: While an ideal recipe for cartilage regeneration is yet to be formulated, it is believed that it will contain cell, biomaterial, and tissue engineering approaches, blended into an effective method for seamless repair of articular cartilage.
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The influence of scaffold elasticity on germ layer specification of human embryonic stem cells
Janeta Zoldan,Emmanouil D. Karagiannis,Christopher Y. Lee,Daniel G. Anderson,Robert Langer,Shulamit Levenberg +5 more
TL;DR: Three dimensional (3D) scaffolds can recapitulate the mechanical stimuli required for directing hESC differentiation and that these stimuli can play a significant role in determining hESCs fate.
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From Lab Bench to Market
TL;DR: Revolutionary advances in tissue engineering are redefining approaches to tissue repair and transplantation through the creation of replacement tissues that remain biointeractive after implantation, imparting physiologic functions as well as structure to the tissue or organ damaged by disease or trauma.
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Transforming growth factor-β in calcium alginate beads for the treatment of articular cartilage defects in the rabbit
Cay M. Mierisch,Steven B. Cohen,Louis C.M. Jordan,Peggy G. Robertson,Gary Balian,David R. Diduch +5 more
TL;DR: Results indicate a significant improvement of the quality of the repair tissue at 6 and 12 weeks with TFG-beta treatment, especially at the lower concentration, and Furthermore, treatment with TGF-beta appears to improve the repair of articular cartilage defects.