Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Micro-systems in biomedical applications
TL;DR: It is concluded that MST has the potential to play a major role in the development of new medical instrumentation and to have a considerable industrial impact in this field.
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Hyaluronan-based polymers in the treatment of osteochondral defects.
Luis A. Solchaga,Jung U. Yoo,Magnus Lundberg,James E. Dennis,Barbara A. Huibregtse,Victor M. Goldberg,Arnold I. Caplan +6 more
TL;DR: The introduction of these hyaluronan‐based polymers into defects provides an appropriate scaffolding and favorable microen‐vironment for the reparative process, and further work is required to fully assess the long‐term outcome of defects treated with these polymers.
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Engineered smooth muscle tissues: regulating cell phenotype with the scaffold.
TL;DR: Three-dimensional smooth muscle-like tissues can be created by culturing SMCs on three-dimensional scaffolds, and that the phenotype of the SMCs is strongly regulated by the scaffold chemistry is demonstrated.
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Active growth factor delivery from poly(d,l-lactide-co-glycolide) foams prepared in supercritical CO2
TL;DR: Residual methylene chloride levels were measured in the foams made with CO(2) and were found to be above the limits imposed by the US Pharmacopoeia implying that further solvent removal would be required prior to in vivo use.
Journal ArticleDOI
Bioreactors for cardiovascular cell and tissue growth: a review.
TL;DR: A review of the current state of the art bioreactors for the generation of tissue engineered cardiovascular devices is presented and the effect of the simulated physiological environment of the bioreactor on tissue development is examined.