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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
- Vol. 260, Iss: 5110, pp 920-926
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.

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Journal ArticleDOI

Stem cells in dentistry – Part II: Clinical applications

TL;DR: Pre-clinical stem cell studies for the regeneration of teeth and other oral organs as well as possible applications of MSC-based immunotherapy in dentistry are outlined and the marketing of stem cell technology in dental stem cell banks with a view toward future regenerative therapies is introduced.
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Regeneration and repair of peripheral nerves with different biomaterials: Review

TL;DR: All of the discoveries in the nerve armamentarium are making their way into the clinic, where they are, showing great potential for improving both the extent and rate of functional recovery compared with alternative nerve guides.
Book ChapterDOI

Hydrogels for musculoskeletal tissue engineering

TL;DR: The primary developments in this field comprise formulation of biomimetic hydrogels incorporating specific biochemical and biophysical cues so as to mimic the natural ECM, design strategies for cell-mediated degradation of scaffolds, techniques for achieving in situ gelation which allow minimally invasive administration of cell-laden hydrogel into the defect site, scaffold-mediated differentiation of adult and embryonic stem cells, and the integration of tissue-engineered "biological implants with the native tissue.
Journal ArticleDOI

A Perspective on the Clinical Translation of Scaffolds for Tissue Engineering

TL;DR: The design constraints of scaffold design are outlined and creative and emerging strategies to overcome limitations and modulate scaffold properties for optimal regeneration are highlighted.
Journal ArticleDOI

Continuous processing of low-density, microcellular poly(lactic acid) foams with controlled cell morphology and crystallinity

TL;DR: In this paper, a continuous processing of poly(lactic acid) foams with a microcellular structure, a high expansion ratio, and varied microcell morphology and crystallinity is reported.
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