Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Synthesis and characterization of hierarchically macroporous and mesoporous CaO-MO-SiO(2)-P(2)O(5) (M=Mg, Zn, Sr) bioactive glass scaffolds.
TL;DR: The gradual release of Ca, P, Si, Mg, Zn and Sr into the culture medium from these scaffolds contributed to the enhancement of the proliferation and ALP activity of mesenchymal stem cells (MSCs).
Journal ArticleDOI
Bioprinting for Neural Tissue Engineering.
TL;DR: A range of bioprinted neural tissue models are reviewed and discussed how they can be used to observe how neurons behave, understand disease processes, develop new therapies and, ultimately, design replacement tissues.
Journal ArticleDOI
Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface.
Hidenori Otsuka,Hidenori Otsuka,Akihiro Hirano,Yukio Nagasaki,Teruo Okano,Yasuhiro Horiike,Yasuhiro Horiike,Kazunori Kataoka +7 more
TL;DR: A two-dimensional microarray of ten thousand (100 x 100) hepatocyte heterospheroids, underlaid with endothelial cells, was successfully constructed with 100 microm spacing in an active area of 20 x 20 mm on microfabricated glass substrates that were coated with poly(ethylene glycol) brushes as mentioned in this paper.
Journal ArticleDOI
Formation of a mandibular condyle in vitro by tissue engineering
Harutsugi Abukawa,Hidetomi Terai,Didier Hannouche,Joseph P. Vacanti,Leonard B. Kaban,Maria J. Troulis +5 more
TL;DR: In this paper, a porcine mandibular condyle was made and used to fabricate porous polymer scaffolds from biodegradable poly DL -lactic-co-glycolic acid (PLGA).
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Injectable gellan gum hydrogels with autologous cells for the treatment of rabbit articular cartilage defects.
João T. Oliveira,Leandro S. Gardel,Leandro S. Gardel,Tommaso Rada,Luis F. Martins,Manuela E. Gomes,Rui L. Reis +6 more
TL;DR: Gellan gum hydrogels combined with autologous cells constitute a promising approach for the treatment of articular cartilage defects, and adipose derived cells may constitute a valid alternative to currently used articular chondrocytes.