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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
- Vol. 260, Iss: 5110, pp 920-926
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.

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A biodegradable hybrid sponge nested with collagen microsponges.

TL;DR: Use of the PLGA sponge as a skeleton facilitated formation of the hybrid sponge into desired shapes with high mechanical strength while collagen microsponges contributed good cell interaction and hydrophilicity.
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Biodegradable polymer composite grafts promote the survival and differentiation of retinal progenitor cells.

TL;DR: It is concluded that biodegradable polymer/progenitor cell composite grafts provide an effective means of increasing progenitor cell survival and overall yield when transplanting to sites within the central nervous system such as the retina.
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Mesenchymal stem cells: lineage, plasticity, and skeletal therapeutic potential.

TL;DR: Critical in the development of this field will be an understanding of the phenotype, plasticity, and potentiality of these cells and the tempering of patients’ expectations driven by commercial and media hype to match current laboratory and clinical observations.
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Cell adhesion biomaterial based on mussel adhesive protein fused with RGD peptide.

TL;DR: The new recombinant fp-151-RGD is suitable for use as a cell-adhesion material in cell culture or tissue engineering, and in any other area where efficient cell adhesion is required.
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