Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model
Takeshi Ohki,Masayuki Yamato,Daisuke Murakami,Ryo Takagi,Joseph Yang,Hideo Namiki,Teruo Okano,Ken Takasaki +7 more
TL;DR: Findings in a clinically relevant canine model show the effectiveness of a novel combined endoscopic approach for the potential treatment of oesophageal cancers that can effectively enhance wound healing and possibly prevent postoperative oesphageal stenosis.
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Characterization of a novel polymeric scaffold for potential application in tendon/ligament tissue engineering.
TL;DR: A novel, biodegradable nano-microfibrous polymer scaffold is developed by electrospinning PLGA nanofibers onto a knitted PLGA scaffold to provide a large biomimetic surface for cell attachment and promote cell proliferation, function, and differentiation.
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Technology insight: adult stem cells in cartilage regeneration and tissue engineering
TL;DR: Adult mesenchymal stem-cell-based tissue engineering is a promising technology for the development of a transplantable cartilage replacement to improve joint function.
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Cell sheet engineering
TL;DR: The use of heterogeneously layered cell sheets are being examined to create laminar structures that resemble the functional and structural units of complex organs such as the liver and kidney.
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Tissue engineering of bone
TL;DR: Important aspects, such as osteogenic cells, matrix materials, inter- and intra-cellular communication, growth factors, gene therapy and current concepts of bone tissue engineering are reviewed and first clinical applications are discussed.