Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Culture of organized cell communities.
TL;DR: Organized cell communities are defined as three-dimensional in vitro grown cell-polymer constructs that display important structural and functional features of the natural tissue that can potentially serve as tissue equivalents for in vivo transplantation.
Journal ArticleDOI
Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels.
Wenqian Xiao,Jiankang He,Jiankang He,Jiankang He,Jason W. Nichol,Jason W. Nichol,Lianyong Wang,Lianyong Wang,Lianyong Wang,Che B. Hutson,Che B. Hutson,Ben Wang,Ben Wang,Yanan Du,Yanan Du,Hongsong Fan,Ali Khademhosseini,Ali Khademhosseini +17 more
TL;DR: A newly synthesized photocrosslinkable interpenetrating polymer network (IPN) hydrogel based on gelatin methacrylate and silk fibroin formed by sequential polymerization is described, which possesses tunable structural and biological properties.
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A composite of hydroxyapatite with electrospun biodegradable nanofibers as a tissue engineering material.
Yoshihiro Ito,Hirokazu Hasuda,Masanobu Kamitakahara,Chikara Ohtsuki,Masao Tanihara,Inn-Kyu Kang,Oh Hyeong Kwon +6 more
TL;DR: The surface of the nanofibrous film showed enhanced cell adhesion over that of the flat film, althoughcell adhesion was not significantly affected by the combination with HAp, and the degradation rate of HAp/PHBV nan ofibrous films in the presence of polyhydroxybutyrate depolymerase was very fast.
Journal ArticleDOI
Synthesis of cross-linked poly(aldehyde guluronate) hydrogels
TL;DR: Sodium poly(guluronate) was isolated, oxidized with sodium periodate, and cross-linked with adipic dihydrazide to yield hydrogels with a wide range of mechanical properties, and with cell adhesion peptides coupled to their backbones.
Journal ArticleDOI
Delivery of Nucleic Acids via Disulfide‐Based Carrier Systems
TL;DR: In this review, emphasis is placed on the biological rationale for the synthesis of redox sensitive, disulfide‐based carrier systems, as well as the extra‐ and intracellular processing of macromolecules containing disulfides.