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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
- Vol. 260, Iss: 5110, pp 920-926
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.

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Osteoinductive biomaterials--properties and relevance in bone repair.

TL;DR: Cell‐ and growth‐factor based tissue engineering provides a promising alternative to natural bone grafts; however, the performance of tissue‐engineered constructs often depends on the used carrier.
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Electrospun silk biomaterial scaffolds for regenerative medicine

TL;DR: This review covers research related to electrospinning of silk, including process parameters, post treatment of the spun fibers, functionalization of nanofibers, and the potential applications for these material systems in regenerative medicine.
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Functional Supramolecular Polymers for Biomedical Applications

TL;DR: The trends and representative achievements in the design and synthesis of supramolecular polymers with specific functions are summarized, as well as their wide‐ranging biomedical applications such as drug delivery, gene transfection, protein delivery, bioimaging and diagnosis, tissue engineering, and biomimetic chemistry are summarized.
Journal ArticleDOI

Phase separation, pore structure, and properties of nanofibrous gelatin scaffolds

TL;DR: A processing technique has been developed to create 3D nanofibrous gelatin (NF-gelatin) scaffolds, which mimic both the physical architecture and the chemical composition of natural collagen, which are excellent scaffolds for tissue engineering.
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Heparin Binding Nanostructures to Promote Growth of Blood Vessels

TL;DR: Heparin, a biopolymer that binds to angiogenic growth factors, was used to nucleate the self-assembly of nanostructures from designed peptide amphiphile molecules, which yields rigid nanofibers that display heparin chains to orient proteins for cell signaling.
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