Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
About:
This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
Citations
More filters
Journal ArticleDOI
Biomimetic hydrogels with pro-angiogenic properties
James J. Moon,Jennifer E. Saik,Ross A. Poché,Julia E. Leslie-Barbick,Soo-Hong Lee,April A. Smith,Mary E. Dickinson,Jennifer L. West +7 more
TL;DR: Developing of synthetic, biomimetic hydrogels that allow the rapid formation of a stable and mature vascular network both in vitro and in vivo are reported, indicating that they may be useful for applications in basic biological research, tissue engineering, and regenerative medicine.
Journal ArticleDOI
Increasing fibroblast response to materials using nanotopography: Morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands
Matthew J. Dalby,Stephen J. Yarwood,Mathis O. Riehle,Heather J H Johnstone,Stanley Affrossman,Adam S. G. Curtis +5 more
TL;DR: The results show that the cells respond to the islands by broad gene up-regulation, notably in the areas of cell signaling, proliferation, cytoskeleton, and production of extracellular matrix proteins, and microscopical results provide confirmation of the microarray findings.
Journal ArticleDOI
Surface hydrolysis of poly(glycolic acid) meshes increases the seeding density of vascular smooth muscle cells
TL;DR: Results demonstrate that optimization of biomaterial-cell interactions provides a strategy for increasing the initial cell seeding density for the engineering of tissues of high cell density.
Journal ArticleDOI
High-strength silk protein scaffolds for bone repair
TL;DR: Development of a high compressive strength polymeric bone composite materials is reported, based on silk protein-protein interfacial bonding, which favored human bone marrow-derived mesenchymal stem cell differentiation toward bone-like tissue in vitro based on biochemical and gene expression for bone markers.
Journal ArticleDOI
Silk protein-based hydrogels: Promising advanced materials for biomedical applications
Sonia Kapoor,Subhas C. Kundu +1 more
TL;DR: This review provides overview of the advances in silk protein-based hydrogels with a primary emphasis on hydrogel of fibroin with the aim of highlighting the research that has been done in the area of silk-basedHydrogels.