Open AccessJournal Article
Tissue engineering : Frontiers in biotechnology
R. Langer,J. P. Vacanti +1 more
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.read more
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Calcium orthophosphate bioceramics
TL;DR: Current biomedical applications of CaPO4-based bioceramics include bone augmentations, artificial bone grafts, maxillofacial reconstruction, spinal fusion, periodontal disease repairs and bone fillers after tumor surgery, and future applications comprise drug delivery and tissue engineering purposes.
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Regenerative biomaterials that "click": simple, aqueous-based protocols for hydrogel synthesis, surface immobilization, and 3D patterning.
TL;DR: In this review, the synthesis and application of regenerative biomaterials via click chemistry are summarized, with particular emphasis on the copper(I)-catalyzed alkyne-azide cycloaddition, Diels-Alder cycloadedditions, and thiol-click coupling.
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Enhanced biological stability of collagen porous scaffolds by using amino acids as novel cross-linking bridges.
TL;DR: In vitro assessment of the biological stability of the cross-linked collagen scaffolds found that the collagenase biodegradation degree was greatly decreased when lysine was added, resulting in a more biological stable scaffold, and scanning electron microscopy measurements prove that the three-dimensional structure of the scaffolds was largely preserved.
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Synthesis of biodegradable poly(propylene fumarate) networks with poly(propylene fumarate)–diacrylate macromers as crosslinking agents and characterization of their degradation products
TL;DR: In this paper, a biodegradable poly(propylene fumarate)-based polymer networks have been prepared by radical polymerization using poly(probylene fumararate) (PPF) and poly(polypropylene-fumarate)-diacrylate (PF-DA) macromers.
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Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage.
Jennifer H. Elisseeff,Kristi S. Anseth,Derek Sims,Winnette McIntosh,Mark A. Randolph,Michael J. Yaremchuk,Robert Langer +6 more
TL;DR: This study demonstrates the potential use of transdermal photopolymerization for minimally invasive subcutaneous implantation of hydrogels and chondrocytes for in vivo cartilage regeneration.