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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
- Vol. 260, Iss: 5110, pp 920-926
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This article is published in Science.The article was published on 1993-01-01 and is currently open access. It has received 5981 citations till now.

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Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps

TL;DR: Direct stamping of human osteoblasts can be used to control the size, spacing, and geometry of patterns of cells printed on porous tissue engineering substrates and may find use in controlling the spatial invasion of scaffolds, promoting the hierarchical organization of cells, and in controlling cell-cell interactions as a step in preservation of phenotypes of cells.
Journal ArticleDOI

Achieving the ideal properties for vascular bypass grafts using a tissue engineered approach: a review

TL;DR: The latest tissue engineering approaches used to give the favourable properties of mechanical strength, arterial compliance, low thrombogenicity, long-term resistance towards biodegradation as well as technological advances which shorten the time required for production of an implantable graft are reviewed.
Journal ArticleDOI

Collagen-based implants reinforced by chitin fibres in a goat shank bone defect model

TL;DR: The results indicated that nHACP implants, both with and without chitin fibres, are better for repairing the defects than pure PLLA, however, only the reinforced implants showed nearly perfect recovery in 15 weeks after operation, so, the reinforced scaffold might be a candidate for bone tissue repair.
Journal ArticleDOI

Cells for tissue engineering.

TL;DR: The use of cultured stem and/or progenitor cells has the potential to improve the extent of regeneration, and also increases the likelihood that the transplanted tissue will integrate with the surrounding tissue.
Journal ArticleDOI

An in situ forming collagen–PEG hydrogel for tissue regeneration

TL;DR: Data suggest that these collagen and PEG hydrogels exhibit the mechanical, physical and biological properties suitable for use as an injectable tissue scaffold for the treatment of a variety of simple and complex tissue defects.
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