Antonio Barrientos

TL;DR: It is demonstrated that SLC25A46, like Ugo1, is a modified carrier protein that has been recruited to the outer mitochondrial membrane and interacts with the inner membrane remodeling protein mitofilin (Fcj1).

TL;DR: Unified criteria for the definition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria are proposed.

TL;DR: This chapter presents an easy, fast and reliable method to in vivo radiolabel mitochondrial translation products from this fission yeast.

TL;DR: MTH1 functional redundancy, existing to different extents in all cancer lines and human tumors evaluated in the study, is a thus far undefined factor which is likely to be critical in understanding the importance of MTH1 and its clinical targeting in cancer.

TL;DR: The efforts to create and characterize yeast models of neurodegeneration using the chronological life span model of aging, and the specific information they can provide regarding the chronology of physiological events leading to neurotoxic proteotoxicity-induced cell death and the identification of new pathways involved are reviewed.