P
Patrick Rockenfeller
Researcher at University of Graz
Publications - 23
Citations - 1921
Patrick Rockenfeller is an academic researcher from University of Graz. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 13, co-authored 21 publications receiving 1534 citations. Previous affiliations of Patrick Rockenfeller include Witten/Herdecke University & University of Kent.
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Journal ArticleDOI
Cardioprotection and lifespan extension by the natural polyamine spermidine
Tobias Eisenberg,Mahmoud Abdellatif,Sabrina Schroeder,Uwe Primessnig,Uwe Primessnig,Slaven Stekovic,Tobias Pendl,Alexandra Harger,Alexandra Harger,Julia Schipke,Andreas Zimmermann,Albrecht Schmidt,Mingming Tong,Christoph Ruckenstuhl,Christopher Dammbrueck,Angelina S. Gross,Viktoria Herbst,Christoph Magnes,Gert Trausinger,Sophie H. Narath,Andreas Meinitzer,Zehan Hu,Zehan Hu,Alexander H. Kirsch,Kathrin Eller,Didac Carmona-Gutierrez,Sabrina Büttner,Sabrina Büttner,Federico Pietrocola,Oskar Knittelfelder,Emilie Schrepfer,Patrick Rockenfeller,Patrick Rockenfeller,Corinna Simonini,Alexandros Rahn,Marion Horsch,Kristin Moreth,Johannes Beckers,Helmut Fuchs,Valerie Gailus-Durner,Frauke Neff,Dirk Janik,Birgit Rathkolb,Jan Rozman,Martin Hrabé de Angelis,Tarek Moustafa,Tarek Moustafa,Guenter Haemmerle,Manuel Mayr,Peter Willeit,Peter Willeit,Marion von Frieling-Salewsky,Burkert Pieske,Burkert Pieske,Luca Scorrano,Thomas R. Pieber,Thomas R. Pieber,Raimund Pechlaner,Johann Willeit,Stephan J. Sigrist,Stephan J. Sigrist,Wolfgang A. Linke,Christian Mühlfeld,Junichi Sadoshima,Joern Dengjel,Joern Dengjel,Stefan Kiechl,Guido Kroemer,Simon Sedej,Frank Madeo +69 more
TL;DR: It is shown that oral supplementation of the natural polyamine spermidine extends the lifespan of mice and exerts cardioprotective effects, reducing cardiac hypertrophy and preserving diastolic function in old mice, and suggests a new and feasible strategy for protection against cardiovascular disease.
Journal ArticleDOI
Phosphatidylethanolamine positively regulates autophagy and longevity.
Patrick Rockenfeller,Michal Koska,Federico Pietrocola,Nadège Minois,Oskar Knittelfelder,Valentina Sica,Joakim Franz,Didac Carmona-Gutierrez,Guido Kroemer,Frank Madeo +9 more
TL;DR: It is shown that the abundance of phosphatidylethanolamine positively regulates autophagy and that organismal life or healthspan could be positively influenced by the consumption of ethanolamine-rich food.
Journal ArticleDOI
The Salmonella effector protein PipB2 is a linker for kinesin-1.
Thomas Henry,Carole Couillault,Patrick Rockenfeller,Emmanuel Boucrot,Audrey Dumont,Nina Schroeder,Aurélie Hermant,Leigh A. Knodler,Patrick Lécine,Olivia Steele-Mortimer,Jean-Paul Borg,Jean-Pierre Gorvel,Stéphane Méresse +12 more
TL;DR: The data indicate that the TTSS-2-mediated fine-tuning of kinesin-1 activity associated with the bacterial vacuole is crucial for the virulence of Salmonella.
Journal ArticleDOI
Unsaturated fatty acids induce non‐canonical autophagy
Mireia Niso-Santano,Mireia Niso-Santano,Shoaib Ahmad Malik,Federico Pietrocola,José Manuel Bravo-San Pedro,José Manuel Bravo-San Pedro,Guillermo Mariño,Guillermo Mariño,Valentina Cianfanelli,Amena BenYounès,Amena BenYounès,Rodrigo Troncoso,Maria Markaki,Valentina Sica,V. Izzo,V. Izzo,Kariman Chaba,Chantal Bauvy,Chantal Bauvy,Nicolas Dupont,Nicolas Dupont,Oliver Kepp,Oliver Kepp,Patrick Rockenfeller,Heimo Wolinski,Frank Madeo,Sergio Lavandero,Patrice Codogno,Patrice Codogno,Francis Harper,Francis Harper,Gérard Pierron,Gérard Pierron,Nektarios Tavernarakis,Nektarios Tavernarakis,Francesco Cecconi,Maria Chiara Maiuri,Maria Chiara Maiuri,Lorenzo Galluzzi,Guido Kroemer +39 more
TL;DR: Unsaturated fatty acids induce a non‐canonical, phylogenetically conserved, autophagic response that in mammalian cells relies on the Golgi apparatus, and downregulation of BECN1 and PIK3C3 abolished palmitate‐ induced, but not oleate‐induced, Autophagy in human cancer cells.
Journal ArticleDOI
Guidelines and recommendations on yeast cell death nomenclature
Didac Carmona-Gutierrez,Maria A. Bauer,Andreas Zimmermann,Andrés Aguilera,Nicanor Austriaco,Kathryn R. Ayscough,Rena Balzan,Shoshana Bar-Nun,Antonio Barrientos,Peter Belenky,Marc Blondel,Ralf J. Braun,Michael Breitenbach,William Wc Burhans,Sabrina Büttner,Sabrina Büttner,Duccio Cavalieri,Michael Chang,Katrina Kf Cooper,Manuela Côrte-Real,Vítor Costa,Vítor Costa,Christophe Cullin,Ian W. Dawes,Jörn Dengjel,Martin Mb Dickman,Tobias Eisenberg,Birthe Fahrenkrog,Nicolas Fasel,Kai-Uwe Fröhlich,Ali Gargouri,Sergio Giannattasio,Paola Goffrini,Campbell W. Gourlay,Chris M. Grant,Michael Mt Greenwood,Nicoletta Guaragnella,Thomas Heger,Jürgen J. Heinisch,Eva Herker,Johannes M. Herrmann,Sebastian J. Hofer,Antonio Jiménez-Ruiz,Helmut Jungwirth,Katharina Kainz,Dimitrios P. Kontoyiannis,Paula Ludovico,Paula Ludovico,Stéphen Manon,Enzo Martegani,Cristina Mazzoni,Lynn La Megeney,Lynn La Megeney,Christa Meisinger,Jens Nielsen,Jens Nielsen,Thomas Nyström,Heinz Hd Osiewacz,Tiago Tf Outeiro,Hay-Oak Park,Tobias Pendl,Dina Petranovic,Stéphane Picot,Peter Polčic,Ted Powers,Mark Ramsdale,Mark Rinnerthaler,Patrick Rockenfeller,Patrick Rockenfeller,Christoph Ruckenstuhl,Raffael Schaffrath,María Segovia,Fedor Ff Severin,Amir Sharon,Stephan J. Sigrist,Cornelia Sommer-Ruck,Maria João Sousa,Johan Jm Thevelein,Karin Thevissen,Vladimir I. Titorenko,Michel Mb Toledano,Mick F. Tuite,F-Nora Vögtle,Benedikt Westermann,Joris Winderickx,Silke Wissing,Stefan Wölfl,Zhaojie J Zhang,Richard Y. Zhao,Bing Zhou,Lorenzo Galluzzi,Lorenzo Galluzzi,Guido Kroemer,Frank Madeo +93 more
TL;DR: Unified criteria for the definition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria are proposed.