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Jörn Dengjel

Researcher at University of Fribourg

Publications -  146
Citations -  11256

Jörn Dengjel is an academic researcher from University of Fribourg. The author has contributed to research in topics: Autophagy & Phosphorylation. The author has an hindex of 40, co-authored 136 publications receiving 8952 citations. Previous affiliations of Jörn Dengjel include University of Freiburg & University of Tübingen.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

Jörn Dengjel, +13 more
- 31 May 2005 - 
TL;DR: This study illustrates a profound influence of autophagy on the class II peptide repertoire and suggests that this finding has implications for the regulation of CD4+ T cell-mediated processes.
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Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

Monique Gannagé, +15 more
- 22 Oct 2009 - 
TL;DR: It is proposed that influenza A virus is able to determine the death of its host cell by inducing apoptosis and also by blocking macroautophagy, a cellular process known to be manipulated by diverse pathogens.
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Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.

Slaven Stekovic, +34 more
- 03 Sep 2019 - 
TL;DR: It is shown that 4 weeks of strict alternate day fasting (ADF) improved markers of general health in healthy, middle-aged humans while causing a 37% calorie reduction on average, and supports its safety.
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Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.

Tobias Eisenberg, +41 more
- 04 Mar 2014 - 
TL;DR: It is shown that nucleocytosolic acetyl-coenzyme A (AcCoA) production is a metabolic repressor of autophagy during aging in yeast, and brain-specific knockdown of Drosophila AcCoA synthetase was sufficient to enhance autophagic protein clearance and prolong lifespan.