K
Kumaraswamynaidu Chitrala
Researcher at National Institutes of Health
Publications - 3
Citations - 248
Kumaraswamynaidu Chitrala is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Genetic architecture. The author has an hindex of 2, co-authored 3 publications receiving 96 citations.
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Journal ArticleDOI
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.
Ming-Huei Chen,Laura M. Raffield,Abdou Mousas,Saori Sakaue,Jennifer E. Huffman,Arden Moscati,Bhavi Trivedi,Tao Jiang,Parsa Akbari,Dragana Vuckovic,Erik L. Bao,Xue Zhong,Regina Manansala,Véronique Laplante,Minhui Chen,Ken Sin Lo,Huijun Qian,Caleb A. Lareau,Mélissa Beaudoin,Karen A. Hunt,Masato Akiyama,Traci M. Bartz,Yoav Ben-Shlomo,Andrew D Beswick,Jette Bork-Jensen,Erwin P. Bottinger,Jennifer A. Brody,Frank J. A. van Rooij,Kumaraswamynaidu Chitrala,Kelly Cho,Hélène Choquet,Adolfo Correa,John Danesh,Emanuele Di Angelantonio,Niki Dimou,Jingzhong Ding,Paul Elliott,Tõnu Esko,Michele K. Evans,James S. Floyd,Linda Broer,Niels Grarup,Michael H. Guo,Andreas Greinacher,Jeffrey Haessler,Torben Hansen,Joanna M. M. Howson,Qin Qin Huang,Wei Huang,Eric Jorgenson,Tim Kacprowski,Mika Kähönen,Yoichiro Kamatani,Masahiro Kanai,Savita Karthikeyan,Fotis Koskeridis,Leslie A. Lange,Terho Lehtimäki,Markus M. Lerch,Allan Linneberg,Yongmei Liu,Leo-Pekka Lyytikäinen,Ani Manichaikul,Hilary C. Martin,Koichi Matsuda,Karen L. Mohlke,Nina Mononen,Yoshinori Murakami,Girish N. Nadkarni,Matthias Nauck,Kjell Nikus,Willem H. Ouwehand,Nathan Pankratz,Oluf Pedersen,Michael Preuss,Bruce M. Psaty,Olli T. Raitakari,David J. Roberts,Stephen S. Rich,Benjamin Rodriguez,Jonathan D. Rosen,Jerome I. Rotter,Petra Schubert,Cassandra N. Spracklen,Praveen Surendran,Hua Tang,Jean-Claude Tardif,Richard C. Trembath,Mohsen Ghanbari,Uwe Völker,Henry Völzke,Nicholas A. Watkins,Alan B. Zonderman,VA Million Veteran Program,Peter W.F. Wilson,Yun Li,Adam S. Butterworth,Jean-François Gauchat,Charleston W. K. Chiang,Bingshan Li,Ruth J. F. Loos,William J. Astle,Evangelos Evangelou,David A. van Heel,Vijay G. Sankaran,Yukinori Okada,Nicole Soranzo,Andrew D. Johnson,Alexander P. Reiner,Paul L. Auer,Guillaume Lettre,Guillaume Lettre +111 more
TL;DR: The clinical significance and predictive value of trans-ethnic variants in multiple populations are explored, genetic architecture and the effect of natural selection on these blood phenotypes between populations are compared and the value of a more global representation of populations in genetic studies is highlighted.
Journal ArticleDOI
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.
Heming Wang,Heming Wang,Raymond Noordam,Brian E. Cade,Brian E. Cade,Karen Schwander,Thomas W. Winkler,Jiwon Lee,Jiwon Lee,Jiwon Lee,Yun Ju Sung,Amy R. Bentley,Alisa K. Manning,Alisa K. Manning,Hugues Aschard,Hugues Aschard,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Marjan Ilkov,Michael R. Brown,Andrea R. V. R. Horimoto,Melissa A. Richard,Traci M. Bartz,Dina Vojinovic,Dina Vojinovic,Elise Lim,Jovia L. Nierenberg,Yongmei Liu,Kumaraswamynaidu Chitrala,Tuomo Rankinen,Solomon K. Musani,Nora Franceschini,Rainer Rauramaa,Maris Alver,Maris Alver,Phyllis C. Zee,Sarah E. Harris,Peter J. van der Most,Ilja M. Nolte,Patricia B. Munroe,Nicholette D. Palmer,Brigitte Kühnel,Stefan Weiss,Wanqing Wen,Kelly A. Hall,Leo-Pekka Lyytikäinen,Jeffrey R. O'Connell,Gudny Eiriksdottir,Lenore J. Launer,Paul S. de Vries,Dan E. Arking,Han Chen,Eric Boerwinkle,Eric Boerwinkle,José Eduardo Krieger,Pamela J. Schreiner,Stephen Sidney,James M. Shikany,Kenneth Rice,Yii-Der Ida Chen,Sina A. Gharib,Joshua C. Bis,Annemarie I. Luik,M. Arfan Ikram,André G. Uitterlinden,Najaf Amin,Hanfei Xu,Daniel Levy,Daniel Levy,Jiang He,Kurt Lohman,Alan B. Zonderman,Treva Rice,Mario Sims,Gregory P. Wilson,Tamar Sofer,Tamar Sofer,Stephen S. Rich,Walter Palmas,Jie Yao,Xiuqing Guo,Jerome I. Rotter,Nienke R. Biermasz,Dennis O. Mook-Kanamori,Lisa W. Martin,Ana Barac,Robert B. Wallace,Daniel J. Gottlieb,Daniel J. Gottlieb,Pirjo Komulainen,Sami Heikkinen,Reedik Mägi,Lili Milani,Andres Metspalu,John M. Starr,Yuri Milaneschi,RJ Waken,Chuan Gao,Melanie Waldenberger,Annette Peters,Konstantin Strauch,Konstantin Strauch,Thomas Meitinger,Till Roenneberg,Uwe Völker,Marcus Dörr,Xiao-Ou Shu,Sutapa Mukherjee,David R. Hillman,Mika Kähönen,Lynne E. Wagenknecht,Christian Gieger,Hans J. Grabe,Wei Zheng,Lyle J. Palmer,Terho Lehtimäki,Vilmundur Gudnason,Alanna C. Morrison,Alexandre C. Pereira,Alexandre C. Pereira,Myriam Fornage,Bruce M. Psaty,Cornelia M. van Duijn,Cornelia M. van Duijn,Ching-Ti Liu,Tanika N. Kelly,Michele K. Evans,Claude Bouchard,Ervin R. Fox,Charles Kooperberg,Xiaofeng Zhu,Timo A. Lakka,Tõnu Esko,Kari E. North,Ian J. Deary,Harold Snieder,Brenda W.J.H. Penninx,W. James Gauderman,Dabeeru C. Rao,Susan Redline,Diana van Heemst +140 more
TL;DR: In this article, the authors performed genome-wide gene by short or long sleep duration interaction analyses on four BP traits across five ancestry groups in two stages using 2 degree of freedom (df) joint test followed by 1df test of interaction effects.
Posted ContentDOI
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Heming Wang,Raymond Noordam,Brian E. Cade,Karen Schwander,Thomas W. Winkler,Jiwon Lee,Yun Ju Sung,Amy R. Bentley,Alisa K. Manning,Hugues Aschard,Tuomas O. Kilpeläinen,Marjan Ilkov,Michael R. Brown,Andrea R. V. R. Horimoto,Melissa A. Richard,Traci M. Bartz,Dina Vojinovic,Elise Lim,Jovia L. Nierenberg,Yongmei Liu,Kumaraswamynaidu Chitrala,Tuomo Rankinen,Solomon K. Musani,Nora Franceschini,Rainer Rauramaa,Maris Alver,Phyllis C. Zee,Sarah E. Harris,Peter J. van der Most,Ilja M. Nolte,Patricia B. Munroe,Nicholette D. Palmer,Brigitte Kühnel,Stefan Weiss,Wanqing Wen,Kelly A. Hall,Leo-Pekka Lyytikäinen,Jeffrey R. O'Connell,Gudny Eiriksdottir,Lenore J. Launer,Paul S. de Vries,Dan E. Arking,Han Chen,Eric Boerwinkle,José Eduardo Krieger,Pamela J. Schreiner,Stephen Sidney,James M. Shikany,Kenneth Rice,Yii-Der Ida Chen,Sina A. Gharib,Joshua C. Bis,Annemarie I. Luik,Mohammad Arfan Ikram,André G. Uitterlinden,Najaf Amin,Hanfei Xu,Daniel Levy,Jiang He,Kurt Lohman,Alan B. Zonderman,Treva Rice,Mario Sims,Gregory P. Wilson,Tamar Sofer,S. S. Rich,Walter Palmas,Jie Yao,Xiuqing Guo,Jerome I. Rotter,Nienke R. Biermasz,Dennis O. Mook-Kanamori,Lisa W. Martin,Ana Barac,Robert B. Wallace,Daniel J. Gottlieb,Pirjo Komulainen,Sami Heikkinen,Reedik Mägi,Lili Milani,Andres Metspalu,John M. Starr,Yuri Milaneschi,RJ Waken,Chuan Gao,Melanie Waldenberger,Annette Peters,Konstantin Strauch,Thomas Meitinger,Till Roenneberg,Uwe Völker,Marcus Dörr,Xiao-Ou Shu,Sutapa Mukherjee,David R. Hillman,Mika Kähönen,Lynne E. Wagenknecht,Christian Gieger,Hans J. Grabe,Wei Zheng,Lyle J. Palmer,Terho Lehtimäki,Vilmundur Gudnason,Alanna C. Morrison,Alexandre C. Pereira,Myriam Fornage,Bruce M. Psaty,Cornelia M. van Duijn,Ching-Ti Liu,Tanika N. Kelly,Michele K. Evans,Claude Bouchard,Ervin R. Fox,Charles Kooperberg,Xiaofeng Zhu,Timo A. Lakka,Tõnu Esko,Kari E. North,Ian J. Deary,Harold Snieder,Brenda W.J.H. Penninx,James Gauderman,Dabeeru C. Rao,Susan Redline,Diana van Heemst +124 more
TL;DR: It is indicated that sleep and primary mechanisms regulating BP may interact to elevate BP level, suggesting novel insights into sleep-related BP regulation.