R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Journal ArticleDOI
A Modular Organization of the Human Intestinal Mucosal Microbiota and Its Association with Inflammatory Bowel Disease
Maomeng Tong,Xiaoxiao Li,Laura Wegener Parfrey,Bennett E. Roth,Andrew Ippoliti,Bo Wei,James Borneman,Dermot P.B. McGovern,Daniel N. Frank,Ellen Li,Steve Horvath,Rob Knight,Rob Knight,Jonathan Braun +13 more
TL;DR: The highly preserved microbial modules accurately classified IBD status of individual patients during disease quiescence, suggesting that microbial dysbiosis in IBD may be an underlying disorder independent of disease activity.
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Global chemical analysis of biology by mass spectrometry
Alexander A. Aksenov,Alexander A. Aksenov,Ricardo Silva,Ricardo Silva,Rob Knight,Norberto Peporine Lopes,Pieter C. Dorrestein +6 more
TL;DR: In a recent review as mentioned in this paper, the authors discuss the informatics and hardware tools available for small-molecule analysis and provide an overview of the tools that could transform how we study the chemistry of biological systems; perhaps in the future this will be as easy as taking a photograph with a smartphone.
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QIIME 2 Enables Comprehensive End-to-End Analysis of Diverse Microbiome Data and Comparative Studies with Publicly Available Data.
Mehrbod Estaki,Lingjing Jiang,Nicholas A. Bokulich,Daniel McDonald,Antonio Gonzalez,Tomasz Kosciolek,Tomasz Kosciolek,Cameron Martino,Qiyun Zhu,Amanda Birmingham,Yoshiki Vázquez-Baeza,Matthew R. Dillon,Evan Bolyen,J. Gregory Caporaso,Rob Knight +14 more
TL;DR: This tutorial analyzes a subset of the Early Childhood Antibiotics and the Microbiome study, which tracked the microbiome composition and development of 43 infants in the United States from birth to 2 years of age, identifying microbiome associations with antibiotic exposure, delivery mode, and diet.
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Collecting Fecal Samples for Microbiome Analyses in Epidemiology Studies
Rashmi Sinha,Jun Chen,Amnon Amir,Emily Vogtmann,Jianxin Shi,Kristin S. Inman,Roberto Flores,Joshua N. Sampson,Rob Knight,Nicholas Chia +9 more
TL;DR: Overall, optimal stability and reproducibility were achieved using FOBT, making this a reasonable sample collection method for 16S analysis, and having standardized method of collecting and storing stable fecal samples will allow future investigations into the role of gut microbiota in chronic disease etiology in large population studies.
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Overview and systematic review of studies of microbiome in schizophrenia and bipolar disorder.
TL;DR: A systematic review of clinical studies of microbiome in schizophrenia and bipolar disorder suggests that these disorders are associated with reduced microbial diversity and show global community differences compared to non-psychiatric comparison samples.