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Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Journal ArticleDOI
Glycan Degradation (GlyDeR) Analysis Predicts Mammalian Gut Microbiota Abundance and Host Diet-Specific Adaptations
Omer Eilam,Raphy Zarecki,Matthew A. Oberhardt,Luke K. Ursell,Martin Kupiec,Rob Knight,Rob Knight,Uri Gophna,Eytan Ruppin +8 more
TL;DR: A novel computational pipeline for modeling glycans degradation (GlyDeR) which predicts the glycan degradation potency of 10,000 reference glycans based on either genomic or metagenomic data and finds a clear connection between microbial gly can degradation and human diet, and suggests a method for the rational design of novel prebiotics.
Journal ArticleDOI
Error minimization and coding triplet/binding site associations are independent features of the canonical genetic code.
TL;DR: Comparing the code error with the coding triplet concentrations in RNA binding sites for eight amino acids shows that these properties are independent and uncorrelated, and error minimization and triplet associations probably arose independently during the history of the genetic code.
Journal ArticleDOI
Toward unrestricted use of public genomic data
Rudolf Amann,Shakuntala Baichoo,Benjamin J. Blencowe,Peer Bork,Mark Borodovsky,Cath Brooksbank,Patrick S. G. Chain,Rita R. Colwell,Daniele Daffonchio,Antoine Danchin,Víctor de Lorenzo,Pieter C. Dorrestein,Robert D. Finn,Claire M. Fraser,Jack A. Gilbert,Steven J. Hallam,Philip Hugenholtz,John P. A. Ioannidis,Janet K. Jansson,Jihyun F. Kim,Hans-Peter Klenk,Martin G. Klotz,Rob Knight,Konstantinos T. Konstantinidis,Nikos C. Kyrpides,Christopher E. Mason,Alice C. McHardy,Folker Meyer,Christos A. Ouzounis,Aristides Patrinos,Mircea Podar,Katherine S. Pollard,Jacques Ravel,Alejandro Reyes Muñoz,Richard J. Roberts,Ramon Rosselló-Móra,Susanna-Assunta Sansone,Patrick D. Schloss,Lynn M. Schriml,João C. Setubal,Rotem Sorek,Rick Stevens,James M. Tiedje,Adrian Turjanski,Gene W. Tyson,David W. Ussery,George M. Weinstock,Owen White,William B. Whitman,Ioannis Xenarios +49 more
TL;DR: It is argued that the publicly available data should be treated as open data, a shared resource with unrestricted use for analysis, interpretation, and publication.
Journal ArticleDOI
The founding charter of the Genomic Observatories Network
Neil M Davies,Neil M Davies,Dawn Field,Linda A. Amaral-Zettler,Melody S. Clark,John Deck,Alexei J. Drummond,Daniel P. Faith,Jonathan B. Geller,Jack A. Gilbert,Jack A. Gilbert,Frank Oliver Glöckner,Frank Oliver Glöckner,Penny R. Hirsch,Jo-Ann Leong,Christopher P. Meyer,Matthias Obst,Serge Planes,Chris Scholin,Alfried P. Vogler,Alfried P. Vogler,Ruth D. Gates,Robert J. Toonen,Véronique Berteaux-Lecellier,Michèle Barbier,Katherine Barker,Stefan Bertilsson,Mesude Bicak,Matthew J. Bietz,Jason Bobe,Levente Bodrossy,Ángel Borja,Jonathan A. Coddington,Jed A. Fuhrman,Gunnar Gerdts,Rosemary G. Gillespie,Kelly D. Goodwin,Paul C. Hanson,Jean-Marc Hero,David Hoekman,Janet K. Jansson,Christian Jeanthon,Rebecca Hufft Kao,Anna Klindworth,Anna Klindworth,Rob Knight,Rob Knight,Renzo Kottmann,Renzo Kottmann,Michelle S. Koo,Georgios Kotoulas,Andrew J. Lowe,Viggo Marteinsson,Folker Meyer,Norman Morrison,David D. Myrold,Evangelos Pafilis,Stephanie M. Parker,J. Jacob Parnell,Paraskevi N. Polymenakou,Sujeevan Ratnasingham,George K. Roderick,Naiara Rodríguez-Ezpeleta,Karsten Schönrogge,Nathalie Simon,Nathalie J. Valette-Silver,Yuri P. Springer,Graham N. Stone,Steve Stones-Havas,Susanna-Assunta Sansone,Kate M Thibault,Patricia Wecker,Antje Wichels,John Wooley,Tetsukazu Yahara,Adriana Zingone +75 more
TL;DR: The co-authors of this paper state their intention to work together to launch the Genomic Observatories Network (GOs Network) for which this document will serve as its Founding Charter, and to describe their shared vision for its future.
Journal ArticleDOI
Niche partitioning of a pathogenic microbiome driven by chemical gradients
Robert A. Quinn,Robert A. Quinn,William Comstock,Tianyu Zhang,James T. Morton,Ricardo Silva,Alda Tran,Alexander A. Aksenov,Alexander A. Aksenov,Louis-Félix Nothias,Daniel Wangpraseurt,Daniel Wangpraseurt,Alexey V. Melnik,Gail Ackermann,Douglas Conrad,Isaac Klapper,Rob Knight,Pieter C. Dorrestein,Pieter C. Dorrestein +18 more
TL;DR: P pH and oxygen strongly partition the microbial community from a diseased human lung into two mutually exclusive communities of pathogens and anaerobes, and these effects were mathematically modeled, enabling a predictive understanding of this complex polymicrobial system.