R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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ConStrains identifies microbial strains in metagenomic datasets
Chengwei Luo,Chengwei Luo,Rob Knight,Rob Knight,Rob Knight,Heli Siljander,Mikael Knip,Ramnik J. Xavier,Dirk Gevers +8 more
TL;DR: ConStrains is presented, an open-source algorithm that identifies conspecific strains from metagenomic sequence data and reconstructs the phylogeny of these strains in microbial communities.
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Postprandial remodeling of the gut microbiota in Burmese pythons
TL;DR: The observed large-scale alterations of the gut microbiota that accompany the Burmese python's own dramatic physiological and morphological changes during feeding and fasting emphasize the need to consider both microbial and host cellular responses to nutrient flux.
Journal ArticleDOI
Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation
Peter A. Crawford,Jan R. Crowley,Nandakumar Sambandam,Brian D. Muegge,Elizabeth K. Costello,Micah Hamady,Rob Knight,Jeffrey I. Gordon +7 more
TL;DR: Benefits provided by the gut microbiota during periods of nutrient deprivation are illustrated, and the importance of further exploring the relationship between gut microbes and cardiovascular health is emphasized.
Journal ArticleDOI
Individuals' diet diversity influences gut microbial diversity in two freshwater fish (threespine stickleback and Eurasian perch)
Daniel I. Bolnick,Lisa K. Snowberg,Philipp E. Hirsch,Philipp E. Hirsch,Christian L. Lauber,Rob Knight,J. Gregory Caporaso,J. Gregory Caporaso,Richard Svanbäck +8 more
TL;DR: It is suggested that multiple diet components can interact non-additively to influence gut microbial diversity, and that individuals with more generalised diets had less diverse microbiota than dietary specialists in both natural and laboratory populations.
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Bacterial colonization and succession in a newly opened hospital
Simon Lax,Simon Lax,Naseer Sangwan,Naseer Sangwan,Daniel P. Smith,Peter E. Larsen,Kim M. Handley,Miles Richardson,Kristina Guyton,Monika A. Krezalek,Benjamin D. Shogan,Jennifer R. DeFazio,Irma Flemming,Baddr A. Shakhsheer,Stephen G. Weber,Emily Landon,Sylvia Garcia-Houchins,Jeffrey A. Siegel,John C. Alverdy,Rob Knight,Brent Stephens,Jack A. Gilbert,Jack A. Gilbert +22 more
TL;DR: It is demonstrated that the patient skin microbial communities were shaped by a diversity of clinical and environmental factors during hospitalization, and that patients initially acquired room-associated taxa that predated their stay but that their own microbial signatures began to influence the room community structure over time.