R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Journal ArticleDOI
Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome
Erin M. Hill-Burns,Justine W. Debelius,James T. Morton,William T. Wissemann,Matthew R. Lewis,Zachary D. Wallen,Shyamal D. Peddada,Stewart A. Factor,Eric Molho,Cyrus P. Zabetian,Rob Knight,Haydeh Payami +11 more
TL;DR: There is mounting evidence for a connection between the gut and Parkinson's disease (PD).
Journal ArticleDOI
Conducting a microbiome study.
Julia K. Goodrich,Sara C. Di Rienzi,Angela C. Poole,Omry Koren,William A. Walters,J. Gregory Caporaso,J. Gregory Caporaso,Rob Knight,Rob Knight,Ruth E. Ley +9 more
TL;DR: A Primer for researchers from diverse disciplines interested in conducting microbiome research discusses factors to be considered in the design, execution, and data analysis of microbiome studies.
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The under-recognized dominance of Verrucomicrobia in soil bacterial communities
Gaddy T. Bergmann,Scott T. Bates,Kathryn G. Eilers,Christian L. Lauber,J. Gregory Caporaso,William A. Walters,Rob Knight,Rob Knight,Noah Fierer +8 more
TL;DR: Analysis of surface soils collected across a range of biomes in Antarctica, Europe, and the Americas shows that Verrucomicrobia appear to be dominant in many soil bacterial communities across the globe, making additional research on their ecology clearly necessary.
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Contamination in Low Microbial Biomass Microbiome Studies: Issues and Recommendations.
Raphael Eisenhofer,Raphael Eisenhofer,Jeremiah J. Minich,Clarisse Marotz,Alan Cooper,Alan Cooper,Rob Knight,Laura S. Weyrich,Laura S. Weyrich +8 more
TL;DR: This work reviews how contaminant DNA and cross-contamination arise within microbiome studies and discusses their negative impacts, especially during the analysis of low microbial biomass samples, and puts forward a set of minimal experimental criteria, the 'RIDE' checklist, to improve the validity of futureLow microbial biomass research.
Journal ArticleDOI
Accurate taxonomy assignments from 16S rRNA sequences produced by highly parallel pyrosequencers
TL;DR: This work uses three large 16S rRNA datasets to test whether taxonomic information based on the full-length sequences can be recaptured by short reads that simulate the pyrosequencer outputs, and finds that different taxonomic assignment methods vary radically in their ability to recapture the taxonomic Information.