R
Rob Knight
Researcher at University of California, San Diego
Publications - 1188
Citations - 322479
Rob Knight is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 201, co-authored 1061 publications receiving 253207 citations. Previous affiliations of Rob Knight include Anschutz Medical Campus & University of Sydney.
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Finding specific RNA motifs: function in a zeptomole world?
Rob Knight,Michael Yarus +1 more
TL;DR: This work has developed a new method for estimating the abundance of any modular (piecewise) RNA motif within a longer random region, and proposes three maxims for easily isolated motifs: the Maxim of Minimization, the maxim of Multiplicity, and theMaxim of the Median.
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The genomic standards consortium: bringing standards to life for microbial ecology.
Pelin Yilmaz,Pelin Yilmaz,Jack A. Gilbert,Jack A. Gilbert,Rob Knight,Linda A. Amaral-Zettler,Ilene Karsch-Mizrachi,Guy Cochrane,Yasukazu Nakamura,Susanna-Assunta Sansone,Frank Oliver Glöckner,Frank Oliver Glöckner,Dawn Field +12 more
TL;DR: This work states that adoption of easy-to-follow standards will vastly improve the ability to interpret data from genomes, metagenomes and marker studies.
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Context-aware dimensionality reduction deconvolutes gut microbial community dynamics.
Cameron Martino,Liat Shenhav,Clarisse Marotz,George Armstrong,Daniel McDonald,Yoshiki Vázquez-Baeza,James T. Morton,Lingjing Jiang,Maria Gloria Dominguez-Bello,Austin D. Swafford,Eran Halperin,Rob Knight +11 more
TL;DR: This work describes a dimensionality reduction tool, compositional tensor factorization (CTF), that incorporates information from the same host across multiple samples to reveal patterns driving differences in microbial composition across phenotypes.
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Structural basis for diversity in the SAM clan of riboswitches
Jeremiah J. Trausch,Zhenjiang Xu,Andrea L. Edwards,Francis E. Reyes,Phillip E. Ross,Rob Knight,Robert T. Batey +6 more
TL;DR: The X-ray structure of a member of the SAM-I/IV family containing the alternative “PK-2” subdomain is solved, revealing that this subdomain forms extensive interactions with the helix housing theSAM-binding pocket, including a highly unusual mode of helix packing in which two helices pack in a perpendicular fashion.
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ghost-tree: creating hybrid-gene phylogenetic trees for diversity analyses
Jennifer Fouquier,Jai Ram Rideout,Evan Bolyen,John Chase,Arron Shiffer,Daniel McDonald,Rob Knight,J. Gregory Caporaso,Scott T. Kelley +8 more
TL;DR: The Silva/UNITE-based ghost tree presented here can be easily integrated into existing fungal analysis pipelines to enhance the resolution of fungal community differences and improve understanding of these communities in built environments.